Advances in Noninvasive Carotid Wall Imaging with Ultrasound: A Narrative Review

被引:20
作者
Alexandratou, Maria [1 ]
Papachristodoulou, Angeliki [1 ]
Li, Xin [2 ]
Partovi, Sasan [3 ]
Davidhi, Andjoli [1 ]
Rafailidis, Vasileios [1 ]
Prassopoulos, Panos [1 ]
Kamperidis, Vasileios [4 ]
Koutroulou, Ioanna [5 ]
Tsivgoulis, Georgios [6 ]
Grigoriadis, Nikolaos [5 ]
Krogias, Christos [7 ]
Karapanayiotides, Theodore [5 ]
机构
[1] Aristotle Univ Thessaloniki, AHEPA Univ Hosp Thessaloniki, Dept Clin Radiol, Thessaloniki 54124, Greece
[2] Hosp Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA
[3] Cleveland Clin, Sect Intervent Radiol, Imaging Inst, Main Campus,9500 Euclid Ave, Cleveland, OH 44195 USA
[4] Aristotle Univ Thessaloniki, Ahepa Univ Hosp, Sch Med, Cardiol Dept 1, Thessaloniki 54636, Greece
[5] Aristotle Univ Thessaloniki, Ahepa Univ Hosp, Sch Med, Dept Neurol 2, Thessaloniki 54636, Greece
[6] Natl & Kapodistrian Univ Athens, Attikon Univ Hosp, Sch Med, Dept Neurol 2, Athens 15772, Greece
[7] Ruhr Univ Bochum, Dept Neurol, St Josef Hosp Bochum, D-44801 Bochum, Germany
关键词
carotid; atherosclerosis; ultrasound; contrast-enhanced ultrasound; stroke; CONTRAST-ENHANCED ULTRASOUND; PLAQUE SURFACE-MORPHOLOGY; SHEAR-WAVE ELASTOGRAPHY; C-REACTIVE PROTEIN; INTRAPLAQUE NEOVASCULARIZATION; ATHEROSCLEROTIC PLAQUE; SYMPTOMATIC PATIENTS; ISCHEMIC-STROKE; REAL-TIME; QUANTITATIVE-ANALYSIS;
D O I
10.3390/jcm11206196
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Carotid atherosclerosis is a major cause for stroke, with significant associated disease burden morbidity and mortality in Western societies. Diagnosis, grading and follow-up of carotid atherosclerotic disease relies on imaging, specifically ultrasound (US) as the initial modality of choice. Traditionally, the degree of carotid lumen stenosis was considered the sole risk factor to predict brain ischemia. However, modern research has shown that a variety of other imaging biomarkers, such as plaque echogenicity, surface morphology, intraplaque neovascularization and vasa vasorum contribute to the risk for rupture of carotid atheromas with subsequent cerebrovascular events. Furthermore, the majority of embolic strokes of undetermined origin are probably arteriogenic and are associated with nonstenosing atheromas. Therefore, a state-of-the-art US scan of the carotid arteries should take advantage of recent technical developments and should provide detailed information about potential thrombogenic (/) and emboligenic arterial wall features. This manuscript reviews recent advances in ultrasonographic assessment of vulnerable carotid atherosclerotic plaques and highlights the fields of future development in multiparametric arterial wall imaging, in an attempt to convey the most important take-home messages for clinicians performing carotid ultrasound.
引用
收藏
页数:21
相关论文
共 124 条
[81]   Imaging of the ulcerated carotid atherosclerotic plaque: a review of the literature [J].
Rafailidis, Vasileios ;
Chryssogonidis, Ioannis ;
Tegos, Thomas ;
Kouskouras, Konstantinos ;
Charitanti-Kouridou, Afroditi .
INSIGHTS INTO IMAGING, 2017, 8 (02) :213-225
[82]   Swirling of microbubbles: Demonstration of a new finding of carotid plaque ulceration on contrast-enhanced ultrasound explaining the arterio-arterial embolism mechanism [J].
Rafailidis, Vasileios ;
Charitanti, Afroditi ;
Tegos, Thomas ;
Rafailidis, Dimitrios ;
Chryssogonidis, Ioannis .
CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 2016, 64 (02) :245-250
[83]   Shear wave elastography imaging of carotid plaques: feasible, reproducible and of clinical potential [J].
Ramnarine, Kumar V. ;
Garrard, James W. ;
Kanber, Baris ;
Nduwayo, Sarah ;
Hartshorne, Timothy C. ;
Robinson, Thompson G. .
CARDIOVASCULAR ULTRASOUND, 2014, 12
[84]   Interrelation between plaque surface morphology and degree of stenosis on carotid angiograms and the risk of ischemic stroke in patients with symptomatic carotid stenosis [J].
Rothwell, PM ;
Gibson, R ;
Warlow, CP .
STROKE, 2000, 31 (03) :615-621
[85]   Expansive arterial remodeling of the carotid arteries and its effect on atherosclerotic plaque composition and vulnerability: an in-vivo black-blood 3T CMR study in symptomatic stroke patients [J].
Saam, Tobias ;
Habs, Maximilian ;
Buchholz, Martin ;
Schindler, Andreas ;
Bayer-Karpinska, Anna ;
Cyran, Clemens C. ;
Yuan, Chun ;
Reiser, Maximilian ;
Helck, Andreas .
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE, 2016, 18
[86]   CT and ultrasound in the study of ulcerated carotid plaque compared with surgical results: Potentialities and advantages of multidetector row CT angiography [J].
Saba, L. ;
Caddeo, G. ;
Sanfilippo, R. ;
Montisci, R. ;
Mallarini, G. .
AMERICAN JOURNAL OF NEURORADIOLOGY, 2007, 28 (06) :1061-1066
[87]   Carotid Artery Wall Imaging: Perspective and Guidelines from the ASNR Vessel Wall Imaging Study Group and Expert Consensus Recommendations of the American Society of Neuroradiology [J].
Saba, L. ;
Yuan, C. ;
Hatsukami, T. S. ;
Balu, N. ;
Qiao, Y. ;
DeMarco, J. K. ;
Saam, T. ;
Moody, A. R. ;
Li, D. ;
Matouk, C. C. ;
Johnson, M. H. ;
Jaeger, H. R. ;
Mossa-Basha, M. ;
Kooi, M. E. ;
Fan, Z. ;
Saloner, D. ;
Wintermark, M. ;
Mikulis, D. J. ;
Wasserman, B. A. .
AMERICAN JOURNAL OF NEURORADIOLOGY, 2018, 39 (02) :E9-E31
[88]   Imaging of the Carotid Artery Vulnerable Plaque [J].
Saba, Luca ;
Anzidei, Michele ;
Marincola, Beatrice Cavallo ;
Piga, Mario ;
Raz, Eytan ;
Bassareo, Pier Paolo ;
Napoli, Alessandro ;
Mannelli, Lorenzo ;
Catalano, Carlo ;
Wintermark, Max .
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 2014, 37 (03) :572-585
[89]  
Sabetai MM, 2001, INT ANGIOL, V20, P51
[90]   Reproducibility of computer-quantified carotid plaque echogenicity - Can we overcome the subjectivity? [J].
Sabetai, MM ;
Tegos, TJ ;
Nicolaides, AN ;
Dhanjil, S ;
Pare, GJ ;
Stevens, JM .
STROKE, 2000, 31 (09) :2189-2196