Chemical Design of Biocompatible Iron Oxide Nanoparticles for Medical Applications

被引：406
作者：
Ling, Daishun [1 ,2 ]
Hyeon, Taeghwan [1 ,2 ]
机构：
[1] Seoul Natl Univ, Ctr Nanoparticle Res, IBS, Seoul 151742, South Korea
[2] Seoul Natl Univ, Sch Chem & Biol Engn, Seoul 151742, South Korea
来源：
SMALL | 2013年 / 9卷 / 9-10期
关键词：
chemical design; iron oxide nanoparticles; biocompatibility; toxicity; nanomedicine; SIZE-CONTROLLED SYNTHESIS; AQUEOUS MAGNETIC LIQUIDS; IN-VITRO CYTOTOXICITY; LARGE-SCALE SYNTHESIS; DRUG-DELIVERY; CONTRAST AGENT; QUANTUM DOTS; SUPERPARAMAGNETIC NANOPARTICLES; BIOMEDICAL APPLICATIONS; CELLULAR UPTAKE;
D O I：
10.1002/smll.201202111
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Iron oxide nanoparticles are one of the most versatile and safe nanomaterials used in medicine. Recent progress in nanochemistry enables fine control of the size, crystallinity, uniformity, and surface properties of iron oxide nanoparticles. In this review, the synthesis of chemically designed biocompatible iron oxide nanoparticles with improved quality and reduced toxicity is discussed for use in diverse biomedical applications.
引用
收藏
页码：1450 / 1466
页数：17
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