From 3D Organoids back to 2D Enteroids

被引：26
|
作者：
Braverman, Jonathan [1 ,2 ]
Yilmaz, Omer H. [1 ,2 ,3 ,4 ]
机构：
[1] MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02142 USA
[2] MIT, Dept Biol, 77 Massachusetts Ave, Cambridge, MA 02142 USA
[3] Massachusetts Gen Hosp, Dept Pathol, Boston, MA 02114 USA
[4] Harvard Med Sch, Boston, MA 02114 USA
来源：
DEVELOPMENTAL CELL | 2018年 / 44卷 / 05期
关键词：
INTESTINAL STEM-CELLS; LGR5; MATH1;
D O I：
10.1016/j.devcel.2018.02.016
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
In this issue of Developmental Cell, Thorne et al. (2018) describe a simple, scalable method to culture 2D enteroid monolayers that surprisingly recapitulates many of the features of 3D organoid cultures and in vivo intestinal tissue and can be used for high-throughput microscopy-based experiments.
引用
收藏
页码：533 / 534
页数：2
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