From 3D Organoids back to 2D Enteroids

被引：26

作者：

Braverman, Jonathan ^{[1
,2
]}

Yilmaz, Omer H. ^{[1
,2
,3
,4
]}

机构：

[1] MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02142 USA

[2] MIT, Dept Biol, 77 Massachusetts Ave, Cambridge, MA 02142 USA

[3] Massachusetts Gen Hosp, Dept Pathol, Boston, MA 02114 USA

[4] Harvard Med Sch, Boston, MA 02114 USA

来源：

DEVELOPMENTAL CELL | 2018年 / 44卷 / 05期

关键词：

INTESTINAL STEM-CELLS; LGR5; MATH1;

D O I：

10.1016/j.devcel.2018.02.016

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In this issue of Developmental Cell, Thorne et al. (2018) describe a simple, scalable method to culture 2D enteroid monolayers that surprisingly recapitulates many of the features of 3D organoid cultures and in vivo intestinal tissue and can be used for high-throughput microscopy-based experiments.

引用

页码：533 / 534

页数：2

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