Synthesis of Hollow Silica Microspheres with High-Developed Surface Area Synthesis of Hollow Silica Microspheres

被引：0

作者：

Bei, I. ^{[1
]}

Tolstov, A. ^{[1
]}

Ishchenko, A. ^{[1
]}

机构：

[1] NAS Ukraine, Inst Macromol Chem, Kharkivske Shose 48, UA-02160 Kiev, Ukraine

来源：

TECHNOLOGICAL INNOVATIONS IN SENSING AND DETECTION OF CHEMICAL, BIOLOGICAL, RADIOLOGICAL, NUCLEAR THREATS AND ECOLOGICAL TERRORISM | 2012年

关键词：

Absorbents; Carriers; Controlled release; Silica microspheres;

D O I：

10.1007/978-94-007-2488-4_22

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Hollow silica microspheres (HSM), as efficient drug delivery carriers, were successfully prepared via a facile water-in-oil emulsion method using water glass precursor. The kinetics of drug release in aqueous medium was simulated using water-soluble erythrosine. Hollow silica microspheres show intensive release of active component at the beginning stages of introduction into aqueous (organism-imitating) conditions. Release rate of the model compound decreased and desorption time increased in the follow range: hollow silica microspheres > porous silica microparticles > silica nanoparticles.

引用

页码：215 / 219

页数：5