Prostate cancer stem cell therapy: hype or hope?

被引:7
作者
Masters, J. R. [1 ]
Kane, C. [1 ]
Yamamoto, H. [1 ]
Ahmed, A. [1 ]
机构
[1] UCL, Prostate Canc Res Ctr, Dept Surg, London W1W 7EJ, England
关键词
prostate; stem cells; therapy;
D O I
10.1038/pcan.2008.22
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The stem cell concept of cancer suggests that each cancer contains a small fraction of stem cells responsible for the maintenance and progression of the disease. The implication of this concept is that by targeting and killing the cancer stem cells, it may be possible to improve survival or even cure the disease. Prostate cancer stem cell therapy is a valid goal to aim for, but there are massive hurdles to overcome, even if the concept is shown to be correct.
引用
收藏
页码:316 / 319
页数:4
相关论文
共 50 条
  • [31] Prostate epithelial stem cell culture
    David L. Hudson
    Cytotechnology, 2003, 41 : 189 - 196
  • [32] Platelet rich plasma: hope or hype?
    Yaman, Reena
    Kinard, Theresa N.
    ANNALS OF BLOOD, 2022, 7
  • [33] Prostate epithelial stem cell culture
    Hudson, DL
    CYTOTECHNOLOGY, 2003, 41 (2-3) : 189 - 196
  • [34] Precision medicine in diffuse large B-cell lymphoma: Hype or hope?
    Prasad, Vinay
    EUROPEAN JOURNAL OF CANCER, 2016, 68 : 22 - 26
  • [35] Haplotype Analysis of Prostate Stem Cell Antigen and Association With Prostate Cancer Risk
    Joung, Jae Young
    Lee, Yeon-Su
    Park, Sohee
    Yoon, Hyekyoung
    Lee, Sang Jin
    Park, Weon Seo
    Seo, Ho Kyung
    Chung, Jinsoo
    Kim, Sook-Young
    Hong, Seung-Hyun
    Kim, Jeong Seon
    Lee, Kang Hyun
    JOURNAL OF UROLOGY, 2011, 185 (06) : 2112 - 2118
  • [36] Extinction models for cancer stem cell therapy
    Sehl, Mary
    Zhou, Hua
    Sinsheimer, Janet S.
    Lange, Kenneth L.
    MATHEMATICAL BIOSCIENCES, 2011, 234 (02) : 132 - 146
  • [37] Artificial Intelligence in Digital Pathology for Bladder Cancer: Hype or Hope? A Systematic Review
    Khoraminia, Farbod
    Fuster, Saul
    Kanwal, Neel
    Olislagers, Mitchell
    Engan, Kjersti
    van Leenders, Geert J. L. H.
    Stubbs, Andrew P.
    Akram, Farhan
    Zuiverloon, Tahlita C. M.
    CANCERS, 2023, 15 (18)
  • [38] Stem cell origin of cancer and differentiation therapy
    Sell, S
    CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2004, 51 (01) : 1 - 28
  • [39] Stem Cells Therapy in Multiple Sclerosis - A New Hope for Progressive Forms
    Ayache, S. S.
    Chalah, M. A.
    JOURNAL OF STEM CELLS & REGENERATIVE MEDICINE, 2016, 12 (01): : P49 - P51
  • [40] Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues: Implications for prostate carcinogenesis and progression of prostate cancer
    Zhao, ZG
    Shen, W
    JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 2004, 34 (07) : 414 - 419