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Prostate cancer stem cell therapy: hype or hope?
被引:7
作者:
Masters, J. R.
[1
]
Kane, C.
[1
]
Yamamoto, H.
[1
]
Ahmed, A.
[1
]
机构:
[1] UCL, Prostate Canc Res Ctr, Dept Surg, London W1W 7EJ, England
关键词:
prostate;
stem cells;
therapy;
D O I:
10.1038/pcan.2008.22
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
The stem cell concept of cancer suggests that each cancer contains a small fraction of stem cells responsible for the maintenance and progression of the disease. The implication of this concept is that by targeting and killing the cancer stem cells, it may be possible to improve survival or even cure the disease. Prostate cancer stem cell therapy is a valid goal to aim for, but there are massive hurdles to overcome, even if the concept is shown to be correct.
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页码:316 / 319
页数:4
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