Semiautomatic Radiofrequency Ablation Planning Based on Constrained Clustering Process for Hepatic Tumors

被引:25
作者
Chen, Rendong [1 ]
Jiang, Tian'an [2 ]
Lu, Fang [1 ]
Wang, Kaifeng [3 ]
Kong, Dexing [1 ]
机构
[1] Zhejiang Univ, Sch Math Sci, Hangzhou 310027, Zhejiang, Peoples R China
[2] Zhejiang Univ, Dept Ultrasound, Affiliated Hosp 1, Coll Med, Hangzhou, Zhejiang, Peoples R China
[3] Hangzhou Normal Univ, Affiliated Hosp, Canc Ctr, Hangzhou, Zhejiang, Peoples R China
基金
中国国家自然科学基金;
关键词
Radiofrequency ablation (RFA); treatment planning; 3D visualization; ellipsoidal clustering; optimization; LIVER-TUMORS; REAL-TIME; GUIDANCE; MODEL;
D O I
10.1109/TBME.2017.2712161
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Radiofrequency ablation (RFA) is currently one of the most effective methods for minimally invasive treatment of hepatic tumors. Planning the probe placements is an essential and challenging step in RFA treatment. To completely destroy the tumor with minimum amount of affected native tissue, a new RFA planning system is proposed in this paper. In the proposed planning system, the minimum number of ablations and a conical insertion region for each ablation session are determined automatically. Based on the geometric character of the tumor, a novel clustering algorithm is developed to allow a better layout of the overlapping ablations. For each case, we force the clustering process under the constraint of amanually defined puncture scope, such that all of the needle trajectories are gathered in a reasonable region. Moreover, the proposed planning system enables the clinician to manually choose a proper insertion path inside the conical insertion region to avoid penetrating large vessels or ribs, which is critical in RFA treatment. The proposed planning system was evaluated on 18 CT scan images and two clinical cases. Results implied that the planning system could provide feasible and accurate RFA treatment plans for hepatic tumors.
引用
收藏
页码:645 / 657
页数:13
相关论文
共 34 条
[1]   Principal component analysis [J].
Abdi, Herve ;
Williams, Lynne J. .
WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL STATISTICS, 2010, 2 (04) :433-459
[2]   Trajectory optimization for the planning of percutaneous radiofrequency ablation of hepatic tumors [J].
Baegert, Claire ;
Villard, Caroline ;
Schreck, Pascal ;
Soler, Luc ;
Gangi, Afshin .
COMPUTER AIDED SURGERY, 2007, 12 (02) :82-90
[3]  
Baegert C, 2007, LECT NOTES COMPUT SC, V4792, P676
[4]   Stereotaxy: Breaking the limits of current radiofrequency ablation techniques [J].
Bale, Reto ;
Widmann, Gerlig ;
Stoffner, D. I. Rudolf .
EUROPEAN JOURNAL OF RADIOLOGY, 2010, 75 (01) :32-36
[5]  
Butz T, 2000, LECT NOTES COMPUT SC, V1935, P317
[6]   Large liver tumors: Protocol for radiofrequency ablation and its clinical application in 110 patients - Mathematic model, overlapping mode, and electrode placement process [J].
Chen, MH ;
Yang, W ;
Yan, K ;
Zou, MW ;
Solbiati, L ;
Liu, LB ;
Dai, Y .
RADIOLOGY, 2004, 232 (01) :260-271
[7]   Radio-frequency ablation of liver tumors: Assessment of therapeutic response and complications [J].
Choi, H ;
Loyer, EM ;
DuBrow, RA ;
Kaur, H ;
David, CL ;
Huang, S ;
Curley, S ;
Charnsangavej, C .
RADIOGRAPHICS, 2001, 21 :S41-S54
[8]  
Conn Andrew R, 2009, Introduction to Derivative-Free Optimization
[9]   Anatomic stereotactic catheter ablation on three-dimensional magnetic resonance images in real time [J].
Dickfeld, T ;
Calkins, H ;
Zviman, M ;
Kato, R ;
Meininger, G ;
Lickfett, L ;
Berger, R ;
Halperin, H ;
Solomon, SB .
CIRCULATION, 2003, 108 (19) :2407-2413
[10]   Radiofrequency thermal ablation: Computer analysis of the size of the thermal injury created by overlapping ablations [J].
Dodd, GD ;
Frank, MS ;
Aribandi, M ;
Chopra, S ;
Chintapalli, KN .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2001, 177 (04) :777-782