RNA-directed DNA methylation in plants

被引:33
|
作者
Movahedi, Ali [1 ]
Sun, Weibu [1 ]
Zhang, Jiaxin [1 ]
Wu, Xiaolong [1 ]
Mousavi, Mohaddesseh [1 ]
Mohammadi, Kourosh [1 ]
Yin, Tongming [1 ]
Qiang Zhuge [1 ]
机构
[1] Nanjing Forestry Univ, Coinnovat Ctr Sustainable Forestry Southern China, Nanjing 210037, Jiangsu, Peoples R China
基金
美国国家科学基金会;
关键词
siRNAs; DNA methylation; RdDM; PolIV; PolV; RDM; DRM; ARABIDOPSIS-THALIANA; DE-NOVO; SPLICING FACTORS; POLYMERASES-IV; POL IV; METHYLTRANSFERASES; HETEROCHROMATIN; TRANSCRIPTION; INVOLVEMENT; ARGONAUTES;
D O I
10.1007/s00299-015-1839-0
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
In plants, many small interfering RNAs (siRNAs) direct de novo methylation by DNA methyltransferase. DNA methylation typically occurs by RNA-directed DNA methylation (RdDM), which directs transcriptional gene silencing of transposons and endogenous transgenes. RdDM is driven by non-coding RNAs (ncRNAs) produced by DNA-dependent RNA polymerases IV and V (PolIV and PolV). The production of siRNAs is initiated by PolIV and ncRNAs produced by PolIV are precursors of 24-nucleotide siRNAs. In contrast, ncRNAs produced by PolV are involved in scaffolding RNAs. In this review, we summarize recent studies of RdDM. In particular, we focus on the mechanisms involved in chromatin remodeling by PolIV and PolV.
引用
收藏
页码:1857 / 1862
页数:6
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