Supercritical Fluid Extraction of Usnic Acid from Lichen of Cladonia Genus

被引：14

作者：

Brovko, O. S. ^{[1
]}

Ivakhnov, A. D. ^{[1
,2
]}

Palamarchuk, I. A. ^{[1
]}

Boitsova, T. A. ^{[1
]}

机构：

[1] Russian Acad Sci, Fed Ctr Integrated Arctic Res, Arkhangelsk, Russia

[2] Lomonosov Northern Arctic Fed Univ, Arkhangelsk, Russia

来源：

RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY B | 2017年 / 11卷 / 08期

关键词：

supercritical fluid extraction; secondary lichen metabolites; usnic acid; Cladonia lichen genus; parameters of extraction process; COMPOUND;

D O I：

10.1134/S1990793117080024

中图分类号：

O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];

学科分类号：

070203 ; 070304 ; 081704 ; 1406 ;

摘要：

The process of carbon dioxide supercritical fluid extraction (SFE) of secondary metabolites from the lichen of Cladonia genus is studied. The yield of solid extract during SFE with carbon dioxide is significantly higher than during the extraction with acetone, ethanol, and petroleum ether on the Soxhlet apparatus. The maximum content of the target component-usnic acid (UA)-in the extract (91%, yield-2.5% of absolutely dry raw material) is obtained under pressure of 35 MPa, temperature 40A degrees C, and duration of the process of 40 min. Introduction of cosolvents (acetone, ethanol, methylene chloride) to carbon dioxide increases the yield of the target product to 3%.

引用

页码：1306 / 1311

页数：6

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