Morphology and function of membrane-bound organelles

被引:57
作者
Heald, Rebecca [1 ]
Cohen-Fix, Orna [2 ]
机构
[1] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA
[2] NIDDK, Lab Cell & Mol Biol, NIH, Bethesda, MD 20892 USA
关键词
TO-TUBULE TRANSFORMATION; ENDOPLASMIC-RETICULUM; MAMMALIAN-CELLS; CONTACT SITES; S; CEREVISIAE; ER; MITOCHONDRIA; PROTEINS; NETWORK; YEAST;
D O I
10.1016/j.ceb.2013.10.006
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The cell interior is a busy and crowded place. A large fraction of the cell volume is taken up by organelles that come in a variety of shapes and sizes. These organelles are surrounded by membrane that not only acts as a diffusion barrier, but also provides each organelle with its unique morphology that contributes to its function, often in ways that are poorly understood. Here we discuss recent discoveries on the relationship between organelle structure and function.
引用
收藏
页码:79 / 86
页数:8
相关论文
共 46 条
[1]   Dynamic Assembly of Brambleberry Mediates Nuclear Envelope Fusion during Early Development [J].
Abrams, Elliott W. ;
Zhang, Hong ;
Marlow, Florence L. ;
Kapp, Lee ;
Lu, Sumei ;
Mullins, Mary C. .
CELL, 2012, 150 (03) :521-532
[2]   The dynamin-like GTPase Sey1p mediates homotypic ER fusion in S. cerevisiae [J].
Anwar, Kamran ;
Klemm, Robin W. ;
Condon, Amanda ;
Severin, Katharina N. ;
Zhang, Miao ;
Ghirlando, Rodolfo ;
Hu, Junjie ;
Rapoport, Tom A. ;
Prinz, William A. .
JOURNAL OF CELL BIOLOGY, 2012, 197 (02) :209-217
[3]  
Arnone JT, 2013, NUCLEUS, V4
[4]   MITOCHONDRIAL DYNAMICS [J].
Bereiter-Hahn, Juergen ;
Jendrach, Marina .
INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY, VOL 284, 2010, 284 :1-65
[5]   Curvature, Lipid Packing, and Electrostatics of Membrane Organelles: Defining Cellular Territories in Determining Specificity [J].
Bigay, Joelle ;
Antonny, Bruno .
DEVELOPMENTAL CELL, 2012, 23 (05) :886-895
[6]   Nuclear envelope morphology constrains diffusion and promotes asymmetric protein segregation in closed mitosis [J].
Boettcher, Barbara ;
Marquez-Lago, Tatiana T. ;
Bayer, Mathias ;
Weiss, Eric L. ;
Barral, Yves .
JOURNAL OF CELL BIOLOGY, 2012, 197 (07) :921-937
[7]  
Brewer JW, 2012, BIOCH RES INT, V2012, DOI DOI 10.1155/2012/738471
[8]   DNA breaks and chromosome pulverization from errors in mitosis [J].
Crasta, Karen ;
Ganem, Neil J. ;
Dagher, Regina ;
Lantermann, Alexandra B. ;
Ivanova, Elena V. ;
Pan, Yunfeng ;
Nezi, Luigi ;
Protopopov, Alexei ;
Chowdhury, Dipanjan ;
Pellman, David .
NATURE, 2012, 482 (7383) :53-U70
[9]   The ER in 3D: a multifunctional dynamic membrane network [J].
Friedman, Jonathan R. ;
Voeltz, Gia K. .
TRENDS IN CELL BIOLOGY, 2011, 21 (12) :709-717
[10]   ER Tubules Mark Sites of Mitochondrial Division [J].
Friedman, Jonathan R. ;
Lackner, Laura L. ;
West, Matthew ;
DiBenedetto, Jared R. ;
Nunnari, Jodi ;
Voeltz, Gia K. .
SCIENCE, 2011, 334 (6054) :358-362