Catechin caged lanthanum orthovanadate nanorods for nuclear targeting and bioimaging applications

被引:16
作者
Vairapperumal, Tamilmani [1 ]
Duraipandy, Natarajan [2 ]
Syamala, Kiran Manikantan [2 ]
Sreeram, Kalarical Janardhanan [1 ]
Unni, Nair Balachandran [1 ]
机构
[1] CSIR Cent Leather Res Inst, Chem Lab, Sardar Patel Rd, Madras 600020, Tamil Nadu, India
[2] CSIR Cent Leather Res Inst, Biol Mat Lab, Sardar Patel Rd, Madras 600020, Tamil Nadu, India
关键词
Bioimaging; Catechin; Nuclear target; Nanorods; Vanadate; Tetragonal; LUMINESCENT PROPERTIES; GOLD NANOPARTICLES; ENERGY-TRANSFER; QUANTUM DOTS; IN-VITRO; ENDOCYTOSIS; PHOSPHORS; DELIVERY; CELLS; EU3+;
D O I
10.1016/j.snb.2016.11.111
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Uniform nanocrystalline LaVO4: Eu nanorods have been successfully prepared through a simple solution based hydrothermal process using catechin hydrate as a ligand. Thermogravimetric, CHN, and zeta potential analysis confirmed the coating of catechin hydrate on the surface of LaVO4. The use of Eu3+ ions resulted in a red luminescence of the products, with an emission maximum at 618 nm. Laser flash photolysis of these luminescent nanorods demonstrated a photoluminescent decay time of milliseconds. In vitro assays performed with HaCaT cells validated the feasibility of these nanorods to serve as nuclear nano bioprobe. Nanorods emission was observed in the cells by confocal microscopy. In addition, red emitter nanorods displayed no cytotoxicity over a wide concentration ranging namely 10 mu g-500 mu g by MIT cell viability assay. These results suggest that LaVO4: Eu nanorods possess the potential to serve as a luminescent probe in bioimaging and nuclear targeting applications. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码:700 / 709
页数:10
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