Potent and selective azetidine-based dipeptidyl peptidase IV (DPP IV) inhibitors

被引:0
|
作者
Li, WX
Oliver, E
Rojas, C
Lauter, S
Thomas, B
Belyakov, S
机构
[1] Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USA
[2] Merck & Co Inc, Dept Metab Disorders, Rahway, NJ 07065 USA
来源
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 229卷
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
207-MEDI
引用
收藏
页码:U145 / U146
页数:2
相关论文
共 50 条
  • [31] Inhibition of dipeptidyl peptidase IV (DPP-IV) by tryptophan containing dipeptides
    Nongonierma, Alice B.
    FitzGerald, Richard J.
    FOOD & FUNCTION, 2013, 4 (12) : 1843 - 1849
  • [32] Dual role of dipeptidyl peptidase IV (DPP IV) in angiogenesis and vascular remodeling
    Kitlinska, J
    Lee, EW
    Li, LJ
    Pons, J
    Estes, L
    Zukowska, Z
    DIPEPTIDYL AMINOPEPTIDASES IN HEALTH AND DISEASE, 2003, 524 : 215 - 222
  • [33] Dipeptidyl peptidase IV (DPP IV) and related molecules in type 2 diabetes
    Flatt, Peter R.
    Bailey, Clifford J.
    Green, Brian D.
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2008, 13 : 3648 - 3660
  • [34] TOPICAL ADMINISTRATION OF DIPEPTIDYL PEPTIDASE IV (DPP-IV) INHIBITORS PREVENTS RETINAL NEURODEGENERATION IN EXPERIMENTAL DIABETES
    Hernandez, C.
    Bogdanov, P.
    Sola-Adell, C.
    Sampedro, J.
    Simo-Servat, O.
    Garcia-Ramirez, M.
    Simo, R.
    EUROPEAN JOURNAL OF OPHTHALMOLOGY, 2017, 27 (03) : E113 - E113
  • [35] Docking Study of Novel Pyrrolidine Derivatives as Potential Dipeptidyl Peptidase-IV (DPP-IV) Inhibitors
    Verma, Sant Kumar
    Sharma, Shashi Kant
    Thareja, Suresh
    LETTERS IN DRUG DESIGN & DISCOVERY, 2015, 12 (04) : 284 - 291
  • [36] Topical administration of dipeptidyl peptidase IV (DPP-IV) inhibitors prevents retinal neurodegeneration in experimental diabetes
    Hernandez, Cristina
    Bogdanov, Patricia
    Sola-Adell, Cristina
    Sampedro, Joel
    Valeri, Marta
    Simo-Servat, Olga
    Herance, Raul
    Simo, Rafael
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2017, 58 (08)
  • [37] Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors
    Tsai, Ting-Yueh
    Hsu, Tsu
    Chen, Chiung-Tong
    Cheng, Jai-Hong
    Yeh, Teng-Kuang
    Chen, Xin
    Huang, Chung-Yu
    Chang, Chung-Nien
    Yeh, Kai-Chia
    Hsieh, Su-Huei
    Chien, Chia-Hui
    Chang, Yi-Wei
    Huang, Chih-Hsiang
    Huang, Yu-Wen
    Huang, Chen-Lung
    Wu, Ssu-Hui
    Wang, Min-Hsien
    Lu, Cheng-Tai
    Chao, Yu-Sheng
    Jiaang, Weir-Torn
    BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 17 (06) : 2388 - 2399
  • [38] Discovery of potent and selective orally bioavailable β-substituted phenylalanine derived dipeptidyl peptidase IV inhibitors.
    Edmondson, SD
    Mastracchio, A
    Duffy, JL
    Eiermann, GJ
    He, HB
    Leiting, B
    Leone, JF
    Lyons, KA
    Makarewicz, AM
    Patel, RA
    Petrov, A
    Wu, JK
    Thornberry, NA
    Weber, AE
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 229 : U218 - U218
  • [39] Discovery of potent and selective dipeptidyl peptidase IV inhibitors derived from β-aminoamides bearing subsituted triazolopiperazines
    Kim, Dooseop
    Kowalchick, Jennifer E.
    Brockunier, Linda L.
    Parmee, Emma R.
    Eiermann, George J.
    Fisher, Michael H.
    He, Huaibing
    Leiting, Barbara
    Lyons, Kathryn
    Scapin, Giovanna
    Patel, Sangita B.
    Petrov, Aleksandr
    Pryor, KellyAnn D.
    Roy, Ranabir Sinha
    Wu, Joseph K.
    Zhang, Xiaoping
    Wyvratt, Matthew J.
    Zhang, Bei B.
    Zhu, Lan
    Thornberry, Nancy A.
    Weber, Ann E.
    JOURNAL OF MEDICINAL CHEMISTRY, 2008, 51 (03) : 589 - 602
  • [40] 4-Amino cyclohexylglycine analogues as potent dipeptidyl peptidase IV inhibitors
    Parmee, ER
    He, JF
    Mastracchio, A
    Edmondson, SD
    Colwell, L
    Eiermann, G
    Feeney, WP
    Habulihaz, B
    He, HB
    Kilburn, R
    Leiting, B
    Lyons, K
    Marsilio, F
    Patel, RA
    Petrov, A
    Di Salvo, J
    Wu, JK
    Thornberry, NA
    Weber, AE
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 14 (01) : 43 - 46