Different temperament and character dimensions correlate with panic disorder comorbidity in bipolar disorder and unipolar depression

被引：23

作者：

Mula, Marco ^{[1
]}

Pini, Stefano ^{[1
]}

Monteleone, Palmiero ^{[2
]}

Iazzetta, Paolo ^{[1
]}

Preve, Matteo ^{[1
]}

Tortorella, Alfonso ^{[2
]}

Amato, Emilia ^{[2
]}

Di Paolo, Luca ^{[1
]}

Conversano, Ciro ^{[1
]}

Rucci, Paola ^{[1
]}

Cassano, Giovanni B. ^{[1
]}

Maj, Mario ^{[2
]}

机构：

[1] Univ Pisa, Dept Psychiat Neurobiol Pharmacol & Biotechnol, I-56100 Pisa, Italy

[2] Univ Naples SUN, Dept Psychiat, Naples, Italy

来源：

JOURNAL OF ANXIETY DISORDERS | 2008年 / 22卷 / 08期

关键词：

Bipolar disorder; Panic disorder; Temperament; Comorbidity; Major depression;

D O I：

10.1016/j.janxdis.2008.02.004

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Background: This study aimed to investigate temperament and character correlates of panic disorder (PD) comorbidity in euthymic patients with bipolar disorder (BID) or unipolar depression (UD). Methods: Temperament and character were assessed using the Temperament and Character Inventory Revised (TCI-R) in 181 patients (70 patients with BD-I, 51 patients with BD-II and 60 with UD) in a euthymic state for at least 2 months. Results: PD was diagnosed in 14.3% of BD-I patients, 31.4% of BD-II and 40% of UD. BD patients with PD, when compared with BD patients without PD, had higher scores on harm avoidance (OR = 1.04; 95% CI = 1.02-1.07: p = 0.002). Patients with UD and PD, when compared to patients with UD without PD, had higher scores on social acceptance (OR = 1.27; 95% CI = 1.08-1.49; p = 0.004). Conclusion: Different temperament and character dimensions correlated with PD comorbidity in BD and UD patients, suggesting different underlying pathophysiological mechanisms. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：1421 / 1426

页数：6

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