Tetralogy of Fallot is an Uncommon Manifestation of Warts, Hypogammaglobulinemia, Infections, and Myelokathexis Syndrome

被引：23

作者：

Badolato, Raffaele ^{[1
,2
]}

Dotta, Laura ^{[1
,2
]}

Tassone, Laura ^{[1
,2
]}

Amendola, Giovanni ^{[3
]}

Porta, Fulvio ^{[4
]}

Locatelli, Franco ^{[5
]}

Notarangelo, Lucia D. ^{[4
]}

Bertrand, Yves ^{[6
]}

Bachelerie, Francoise ^{[7
]}

Donadieu, Jean ^{[8
]}

机构：

[1] Pediat Clin, I-25123 Brescia, Italy

[2] A Nocivelli Inst Mol Med, I-25123 Brescia, Italy

[3] Osped Nocera Inferiore, UOC Pediat TIN, Salerno, Italy

[4] Spedali Civil Brescia, UOC Oncoematol Pediat, I-25125 Brescia, Italy

[5] Univ Pavia, Dipartimento Oncoematol Pediat, IRCCS Osped Pediat Bambino Gesu, I-27100 Pavia, Italy

[6] Univ Lyon 1, Hosp Civils Lyon, Inst Hematol & Oncol Pediat, Serv Immuno Hematol Pediat, F-69365 Lyon, France

[7] Univ Paris 11, INSERM, LERMIT, UMR S996, Clamart, France

[8] Hop Trousseau, AP HP, Serv Hemato Oncol Pediat Registre Neutropenies Co, F-75571 Paris, France

来源：

JOURNAL OF PEDIATRICS | 2012年 / 161卷 / 04期

关键词：

CXCR4 ANTAGONIST PLERIXAFOR; CHEMOKINE RECEPTOR; WHIM-SYNDROME; BETA-ARRESTIN; HEMATOPOIESIS; SDF-1/PBSF; DISORDER; CXCL12;

D O I：

10.1016/j.jpeds.2012.05.058

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome is a rare immunodeficiency disorder. We report three patients with WHIM syndrome who are affected by Tetralogy of Fallot (TOF). This observation suggests a possible increased risk of TOF in WHIM syndrome and that birth presentation of TOF and neutropenia should lead to suspect WHIM syndrome. (J Pediatr 2012;161:763-5)

引用

页码：763 / 765

页数：3

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