Impact of placental weight and fetal/placental weight ratio Z score on fetal growth and the perinatal outcome

被引：18

作者：

Matsuda, Yoshio ^{[1
,2
]}

Itoh, Toshiya ^{[3
]}

Itoh, Hiroaki ^{[3
]}

Ogawa, Masaki ^{[4
]}

Sasaki, Kemal ^{[5
]}

Kanayama, Naohiro ^{[3
]}

Matsubara, Shigeki ^{[6
]}

机构：

[1] Mishima Gen Hosp, Japan Community Hlth Care Org JCHO, Dept Obstet & Gynecol, 2276 Yata Aza Fujikubo, Mishima, Shizuoka 4110801, Japan

[2] Int Univ Hlth & Welf Hosp, Dept Obstet & Gynecol, 537-3 Iguchi Nasushiobara, Nasushiobara, Tochigi 3292763, Japan

[3] Hamamatsu Univ Sch Med, Dept Obstet & Gynecol, Higashi Ku, 1-20-1 Handayama, Hamamatsu, Shizuoka 4313192, Japan

[4] Tokyo Womens Med Univ, Dept Obstet & Gynecol, Shinjuku Ku, 8-1 Kawada Cho, Tokyo 1628666, Japan

[5] Yokohama Soei Univ, Fac Childhood Educ, Midori Ku, 1 Miho Cho, Yokohama, Kanagawa 2260015, Japan

[6] Jichi Med Univ, Dept Obstet & Gynecol, 3311-1 Yakushiji, Shimotsuke, Tochigi 3290498, Japan

来源：

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES | 2018年 / 15卷 / 05期

关键词：

appropriate for date; fetal/placental weight ratio(F/P); heavy for date; placental weight; small for date; Z score; GESTATIONAL-AGE; BIRTH-WEIGHT; RISK-FACTORS; SINGLETON; PARITY; RESTRICTION; DELIVERIES; DIFFERENCE; CURVES; GENDER;

D O I：

10.7150/ijms.23107

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective: To classify the infants into 9 blocks based on the deviation of both placental weight (PW) and fetal/placental weight ratio (F/P) Z score and compared the incident rate of perinatal death in each of the small for date (SFD) vs. appropriate for date (AFD) vs. heavy for date (HFD) groups. Methods: The study population consisted of 93,034 placentas/infants from women who vaginally delivered a singleton infant. They were classified into 3 groups according to infants' weight: SFD (n=3,379), AFD (n=81,143) and HFD (n=8,512). The population was classified into 9 blocks according to the combination of i) low vs. middle vs. high placental weight (PW: a sex-, parity-and gestational-age-specific placental weight) and ii) low vs. middle vs. high F/P. In both i) and ii), +/- 1.28 standard deviations in the in the Z scores was used for classifying low vs. middle vs. high, with 3x3 making 9 blocks. We then determined whether or not the perinatal death in each block differed among the three groups (SFD vs. AFD vs. HFD). Results: (1) The proportions of 'balanced growth of placenta and infant' (appropriate PW and F/P based on Z-score) were 37.6% in the SFD group, 78.8% in the AFD group, and 51.2% in HFD group. (2) The proportion of 'inappropriately heavy placenta' in the SFD group and that of 'inappropriately light placenta' in the HFD group were 0.3 and 0.4%, respectively, a very rare phenomenon. The proportions of 'inappropriately heavy placenta' and 'inappropriately light placenta' accounted for 4.1 and 5.5% in AFD group, respectively. (3) The rates of perinatal death in those with 'balanced growth of placenta and infant' were lowest in the SFD and AFD groups. Conclusion: By showing the fact that perinatal death was lowest in cases with balanced fetal/placental growth, we conclude that 9-block categorization of PW and F/P based on deviation in the Z-score may be a candidate factor employable for understanding fetal and placental growth and perinatal deaths.

引用

页码：484 / 491

页数：8

共 22 条

[1] Placenta weight percentile curves for singleton and twins deliveries [J].