PET Radiomics in NSCLC: state of the art and a proposal for harmonization of methodology

被引:137
作者
Sollini, M. [1 ]
Cozzi, L. [1 ,2 ]
Antunovic, L. [3 ]
Chiti, A. [1 ,3 ]
Kirienko, M. [1 ]
机构
[1] Humanitas Univ, Dept Biomed Sci, Via Manzoni 113, I-20089 Milan, Italy
[2] Humanitas Clin & Res Ctr, Radiotherapy & Radiosurg Unit, Via Manzoni 56, I-20089 Milan, Italy
[3] Humanitas Clin & Res Ctr, Nucl Med Unit, Via Manzoni 56, I-20089 Milan, Italy
关键词
POSITRON-EMISSION-TOMOGRAPHY; INTRATUMORAL METABOLIC HETEROGENEITY; VOLUME HISTOGRAM METHOD; TUMOR TEXTURE ANALYSIS; F-18-FDG PET; PROGNOSTIC VALUE; FDG UPTAKE; QUANTITATIVE ASSESSMENT; IMAGING FEATURES; TRACER UPTAKE;
D O I
10.1038/s41598-017-00426-y
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Imaging with positron emission tomography (PET)/computed tomography (CT) is crucial in the management of cancer because of its value in tumor staging, response assessment, restaging, prognosis and treatment responsiveness prediction. In the last years, interest has grown in texture analysis which provides an "in-vivo" lesion characterization, and predictive information in several malignances including NSCLC; however several drawbacks and limitations affect these studies, especially because of lack of standardization in features calculation, definitions and methodology reporting. The present paper provides a comprehensive review of literature describing the state-of-the-art of FDG-PET/CT texture analysis in NSCLC, suggesting a proposal for harmonization of methodology.
引用
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页数:15
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