Diversity-oriented synthesis of novel polycyclic scaffolds using polymer-bound reagents

被引：16

作者：

Garcia-Cuadrado, Domingo ^{[1
]}

Barluenga, Sofia ^{[1
]}

Winssinger, Nicolas ^{[1
]}

机构：

[1] Univ Strasbourg, CNRS, Inst Sci & Ingn Supramol, Lab Chim Organ & Bioorgan, F-67000 Strasbourg, France

来源：

CHEMICAL COMMUNICATIONS | 2008年 / 38期

关键词：

D O I：

10.1039/b807869f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A concise sequence utilizing a Petasis three component reaction followed by a tandem aza-Cope-Mannich cyclization afforded novel polycyclic heterocycles in good yield; alternative iminium cyclization based on a Pictet-Spengler reaction or aminal formation led to divergent pathways affording skeletal diversity.

引用

页码：4619 / 4621

页数：3

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