New developments in the use of positive airway pressure for obstructive sleep apnea

被引:62
作者
Donovan, Lucas M. [1 ]
Boeder, Schafer [2 ]
Malhotra, Atul [3 ]
Patel, Sanjay R. [4 ]
机构
[1] Beth Israel Deaconess Med Ctr, Div Pulm Crit Care & Sleep Med, Boston, MA 02215 USA
[2] Univ Calif San Diego, Dept Med, San Diego, CA 92103 USA
[3] Univ Calif San Diego, Dept Pulm & Crit Care Med, San Diego, CA 92103 USA
[4] Brigham & Womens Hosp, Div Sleep Med, Boston, MA 02115 USA
关键词
Obstructive sleep apnea (OSA); positive airway pressure (PAP); treatment adherence; QUALITY-OF-LIFE; HYPOGLOSSAL-NERVE-STIMULATION; CARDIOVASCULAR RISK-FACTORS; RANDOMIZED CONTROLLED-TRIAL; ADAPTIVE SERVO-VENTILATION; NASAL CPAP THERAPY; HEART-FAILURE; DAYTIME SLEEPINESS; BLOOD-PRESSURE; WEIGHT-LOSS;
D O I
10.3978/j.issn.2072-1439.2015.07.30
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Obstructive sleep apnea (OSA) is a disorder which afflicts a large number of individuals around the world. OSA causes sleepiness and is a major cardiovascular risk factor. Since its inception in the early 1980's, continuous positive airway pressure (CPAP) has emerged as the major treatment of OSA, and it has been shown to improve sleepiness, hypertension, and a number of cardiovascular indices. Despite its successes, adherence with treatment remains a major limitation. Herein we will review the evidence behind the use of positive airway pressure (PAP) therapy, its various modes, and the methods employed to improve adherence. We will also discuss the future of PAP therapy in OSA and personalization of care.
引用
收藏
页码:1323 / 1342
页数:20
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