Synthesis of new derivatives of 5-(3,4-dihydro-2De-pyrrol-5-yl)-pyrimidine

被引：6

作者：

Gasparyan, S. P. ^{[1
,3
]}

Alexanyan, M. V. ^{[1
]}

Arutyunyan, G. K. ^{[1
]}

Kocharov, S. L. ^{[1
]}

Martirosyan, A. H. ^{[1
]}

Tamazyan, R. A. ^{[2
]}

Ayvazyan, A. G. ^{[2
]}

Panosyan, H. A. ^{[2
]}

Danagulyan, G. G. ^{[3
]}

机构：

[1] Mndzhoyan Inst Fine Organ Chem, Yerevan, Armenia

[2] Ctr Mol Struct Res, Pr Azatutyan 26, Yerevan 0014, Armenia

[3] Russian Armenian Slavon Univ, Yerevan, Armenia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2016年 / 52卷 / 11期

关键词：

IMMUNODEFICIENCY-VIRUS TYPE-1; TRANSITION-STATE; C-NUCLEOSIDES; INHIBITORS; OPTIMIZATION; CYCLIZATION; POTENT;

D O I：

10.1134/S1070428016110166

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

By one-stage condensation of 6-(arylamino)pyrimidine-2,4(1De,3De)-diones with pyrrolidin-2-one new potential antiviral compounds were obtained, analogs of pyrrolinylpyrimidine containing structural fragments of known drugs AZT and HEPT used in treating HIV-infections.

引用

页码：1646 / 1653

页数：8

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