Synthesis of new derivatives of 5-(3,4-dihydro-2De-pyrrol-5-yl)-pyrimidine

被引：6
|
作者：
Gasparyan, S. P. [1 ,3 ]
Alexanyan, M. V. [1 ]
Arutyunyan, G. K. [1 ]
Kocharov, S. L. [1 ]
Martirosyan, A. H. [1 ]
Tamazyan, R. A. [2 ]
Ayvazyan, A. G. [2 ]
Panosyan, H. A. [2 ]
Danagulyan, G. G. [3 ]
机构：
[1] Mndzhoyan Inst Fine Organ Chem, Yerevan, Armenia
[2] Ctr Mol Struct Res, Pr Azatutyan 26, Yerevan 0014, Armenia
[3] Russian Armenian Slavon Univ, Yerevan, Armenia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2016年 / 52卷 / 11期
关键词：
IMMUNODEFICIENCY-VIRUS TYPE-1; TRANSITION-STATE; C-NUCLEOSIDES; INHIBITORS; OPTIMIZATION; CYCLIZATION; POTENT;
D O I：
10.1134/S1070428016110166
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
By one-stage condensation of 6-(arylamino)pyrimidine-2,4(1De,3De)-diones with pyrrolidin-2-one new potential antiviral compounds were obtained, analogs of pyrrolinylpyrimidine containing structural fragments of known drugs AZT and HEPT used in treating HIV-infections.
引用
收藏
页码：1646 / 1653
页数：8
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