Hg(II)-Mediated Intramolecular Cyclization Reaction in Aqueous Media and Its Application as Hg(II) Selective Indicator

被引：44

作者：

Atta, Ananta Kumar ^{[1
]}

Kim, Seul-Bi ^{[1
]}

Heo, Jungseok ^{[2
]}

Cho, Dong-Gyu ^{[1
]}

机构：

[1] Inha Univ, Dept Chem, Inchon 402751, South Korea

[2] Chungnam Natl Univ, Dept Chem, Taejon 305764, South Korea

来源：

ORGANIC LETTERS | 2013年 / 15卷 / 05期

基金：

新加坡国家研究基金会;

关键词：

RHODAMINE-BASED FLUORESCENT; HG2+-SELECTIVE CHEMODOSIMETER; HG2+; SENSOR; MERCURY; PROBE;

D O I：

10.1021/ol4000873

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Hg(II)-specific intramolecular cyclization reaction of ethynyl phenols was carried out for the first time in semiaqueous media at ambient temperature. The reaction unit (ethynyl phenol) was coupled with a malononitrile derivative (signal unit), which afforded the chromogenic Hg(II) indicator 7. The reaction of the chromogenic Hg(II) indicator 7 was further optimized in DMSO/water (3:7, v/v) (10 mM PBS buffer, pH = 7.0). Compound 7 displays a color change from blue to pale yellow in the presence of Hg(II).

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收藏

页码：1072 / 1075

页数：4

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共 35 条

[1] FLUOROMETRIC CHEMODOSIMETRY - MERCURY(II) AND SILVER(I) INDICATION IN WATER VIA ENHANCED FLUORESCENCE SIGNALING [J].

CHAE, MY ;

CZARNIK, AW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (24) :9704-9705

[2] A Squaraine-Based Colorimetric and "Turn on" Fluorescent Sensor for Selective Detection of Hg2+ in an Aqueous Medium [J].

Chen, Cheng ;

Wang, Ruyong ;

Guo, Liangqia ;

Fu, Nanyan ;

Dong, Haijun ;

Yuan, Yaofeng .

ORGANIC LETTERS, 2011, 13 (05) :1162-1165

[3] Hg2+ Selective Fluorescent and Colorimetric Sensor: Its Crystal Structure and Application to Bioimaging [J].

Chen, Xiaoqiang ;

Nam, Seong-Won ;

Jou, Min Jung ;

Kim, Youngmee ;

Kim, Sung-Jin ;

Park, Sungsu ;

Yoon, Juyoung .

ORGANIC LETTERS, 2008, 10 (22) :5235-5238

[4] Modern reaction-based indicator systems [J].

Cho, Dong-Gyu ;

Sessler, Jonathan L. .

CHEMICAL SOCIETY REVIEWS, 2009, 38 (06) :1647-1662

[5] Hg2+-selective chromogenic and fluorogenic chemodosimeter based on thiocoumarins [J].

Choi, Myung Gil ;

Kim, Youn Hwan ;

Namgoong, Ji Eun ;

Chang, Suk-Kyu .

CHEMICAL COMMUNICATIONS, 2009, (24) :3560-3562

[6] The chemical form of mercury in fish [J].

Harris, HH ;

Pickering, IJ ;

George, GN .

SCIENCE, 2003, 301 (5637) :1203-1203

[7] DIFFERENTIAL PULSE POLAROGRAPHIC-DETERMINATION OF SOME CARCINOGENIC NITROSAMINES [J].

HASEBE, K ;

OSTERYOUNG, J .

ANALYTICAL CHEMISTRY, 1975, 47 (14) :2412-2418

[8] Histidine Based Fluorescence Sensor Detects Hg2+ in Solution, Paper Strips, and in Cells [J].

Hatai, Joydev ;

Pal, Suman ;

Jose, Gregor P. ;

Bandyopadhyay, Subhajit .

INORGANIC CHEMISTRY, 2012, 51 (19) :10129-10135

[9] Turn-On fluorescent sensor for Hg2+ via displacement approach [J].

He, Guangjie ;

Zhao, Yonggang ;

He, Cheng ;

Liu, Yang ;

Duan, Chunying .

INORGANIC CHEMISTRY, 2008, 47 (12) :5169-5176

[10] A Rhodamine-Based Hg2+ Sensor with High Selectivity and Sensitivity in Aqueous Solution: A NS2-Containing Receptor [J].

Huang, Junhai ;

Xu, Yufang ;

Qian, Xuhong .

JOURNAL OF ORGANIC CHEMISTRY, 2009, 74 (05) :2167-2170

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