Developmental origins of health and adult disease: What should neonatologists/paediatricians be considering about the long-term health of their patients?

被引:19
|
作者
Kent, Alison L. [1 ,2 ]
机构
[1] Canberra Hosp, Dept Neonatol, Woden, ACT 2606, Australia
[2] Australian Natl Univ, Sch Med, Canberra, ACT, Australia
关键词
cardiovascular; developmental origins; metabolic; neonate; premature; CATCH-UP GROWTH; FOR-GESTATIONAL-AGE; LOW-BIRTH-WEIGHT; BODY-MASS INDEX; MATERNAL PROTEIN RESTRICTION; IMPAIRED GLUCOSE-TOLERANCE; SYSTOLIC BLOOD-PRESSURE; REDUCED NEPHRON NUMBER; INSULIN-RESISTANCE; CHILDHOOD GROWTH;
D O I
10.1111/j.1440-1754.2012.02541.x
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The developmental origins of health and disease hypothesis is now strongly supported by both animal and human evidence, and as a consequence, obstetricians, neonatologists and paediatricians need to consider the impact that the in utero and early post-natal environment can have on later renal, cardiovascular and metabolic health. Four common clinical scenarios were provided along with animal and human evidence identifying long-term health implications. Suggestions as to how we should translate this growing body of evidence into practice are provided.
引用
收藏
页码:730 / 734
页数:5
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