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Developmental origins of health and adult disease: What should neonatologists/paediatricians be considering about the long-term health of their patients?
被引:19
|作者:
Kent, Alison L.
[1
,2
]
机构:
[1] Canberra Hosp, Dept Neonatol, Woden, ACT 2606, Australia
[2] Australian Natl Univ, Sch Med, Canberra, ACT, Australia
关键词:
cardiovascular;
developmental origins;
metabolic;
neonate;
premature;
CATCH-UP GROWTH;
FOR-GESTATIONAL-AGE;
LOW-BIRTH-WEIGHT;
BODY-MASS INDEX;
MATERNAL PROTEIN RESTRICTION;
IMPAIRED GLUCOSE-TOLERANCE;
SYSTOLIC BLOOD-PRESSURE;
REDUCED NEPHRON NUMBER;
INSULIN-RESISTANCE;
CHILDHOOD GROWTH;
D O I:
10.1111/j.1440-1754.2012.02541.x
中图分类号:
R72 [儿科学];
学科分类号:
100202 ;
摘要:
The developmental origins of health and disease hypothesis is now strongly supported by both animal and human evidence, and as a consequence, obstetricians, neonatologists and paediatricians need to consider the impact that the in utero and early post-natal environment can have on later renal, cardiovascular and metabolic health. Four common clinical scenarios were provided along with animal and human evidence identifying long-term health implications. Suggestions as to how we should translate this growing body of evidence into practice are provided.
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页码:730 / 734
页数:5
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