An international effort to cure a global health problem: A report on the 19th Hemoglobin Switching Conference

被引：7
作者：
Blobel, Gerd A. [1 ]
Bodine, David [2 ]
Brand, Marjorie [3 ]
Crispino, John [4 ]
de Bruijn, Marella F. T. R. [5 ,6 ]
Nathan, David [7 ,8 ]
Papayannopoulou, Thalia [9 ]
Porcher, Catherine [5 ,6 ]
Strouboulis, John [10 ]
Zon, Len [11 ]
Higgs, Douglas R. [5 ,6 ]
Stamatoyannopoulos, George [9 ]
Engel, James Douglas [12 ]
机构：
[1] Univ Penn, Childrens Hosp Philadelphia, Perelman Sch Med, Div Hematol, Philadelphia, PA 19104 USA
[2] NHGRI, NIH, Bethesda, MD 20892 USA
[3] Ottawa Hosp Res Inst, Sprott Ctr Stem Cell Res, Ottawa, ON, Canada
[4] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Div Hematol Oncol, Chicago, IL 60611 USA
[5] Univ Oxford, John Radcliffe Hosp, Weatherall Inst Mol Med, MRC Mol Haematol Unit, Oxford OX3 9DU, England
[6] Oxford Univ Hosp, NIHR Oxford Biomed Ctr, BRC Blood Theme, Oxford, England
[7] Harvard Univ, Sch Med, Dana Farber Canc Inst,Dept Pediat,Dept Pediat Onc, Div Hematol & Oncol,Boston Childrens Hosp, Boston, MA 02115 USA
[8] Harvard Univ, Sch Med, Dana Farber Canc Inst,Dept Pediat Oncol,Dept Med, Div Hematol & Oncol,Boston Childrens Hosp, Boston, MA 02115 USA
[9] Univ Washington, Sch Med, Dept Med, Seattle, WA 98195 USA
[10] Biomed Sci Res Ctr Alexander Fleming, Div Mol Oncol, Vari, Greece
[11] Boston Childrens Hosp, HHMI, Boston, MA USA
[12] Univ Michigan, Sch Med, Dept Cell & Dev Biol, Ann Arbor, MI USA
来源：
EXPERIMENTAL HEMATOLOGY | 2015年 / 43卷 / 10期
基金：
英国医学研究理事会;
关键词：
CAUSES HEREDITARY PERSISTENCE; FETAL-HEMOGLOBIN; GENE-EXPRESSION; GAMMA-GLOBIN; THERAPY; SINGLE; ADULT; ERYTHROPOIESIS; TRANSCRIPTION; BINDING;
D O I：
10.1016/j.exphem.2015.06.008
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Every 2 years since 1978, an international group of scientists, physicians, and other researchers meet to discuss the latest developments in the underlying etiology, mechanisms of action, and developmental acquisition of cellular and systemic defects exhibited and elicited by the most common inherited human disorders, the hemoglobinopathies. The 19th Hemoglobin Switching Conference, held in September 2014 at St. John's College in Oxford, once again exceeded all expectations by describing cutting edge research in cellular, molecular, developmental, and genomic advances focused on these diseases. The conference comprised about 60 short talks over 3 days by leading investigators in the field. This meeting report describes the highlights of the conference. Copyright (C) 2015 ISEH - International Society for Experimental Hematology. Published by Elsevier Inc.
引用
收藏
页码：821 / 837
页数：17
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