Insights for Stratification of Risk in Brugada Syndrome

被引：9

作者：

Garcia Iglesias, Daniel ^{[1
,2
]}

Rubin, Jose ^{[1
,2
]}

Perez, Diego ^{[1
,2
]}

Moris, Cesar ^{[1
,2
]}

Calvo, David ^{[1
,2
]}

机构：

[1] Hosp Univ Cent Asturias, Dept Cardiol, Arrhythmia Unit, Oviedo, Spain

[2] Inst Invest Sanitaria Principado Asturias, Oviedo, Spain

来源：

EUROPEAN CARDIOLOGY REVIEW | 2019年 / 14卷 / 01期

关键词：

Brugada syndrome; sudden cardiac death; ECG; risk stratification; patient management; PROGRAMMED ELECTRICAL-STIMULATION; ST-SEGMENT ELEVATION; PROGNOSTIC VALUE; VENTRICULAR STIMULATION; NATURAL-HISTORY; CARDIAC-ARREST; J-WAVE; MULTICENTER; ECG; INDIVIDUALS;

D O I：

10.15420/ecr.2018.31.2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Brugada syndrome (BrS) is an inherited disease with an increased risk of sudden cardiac death (SCD). However, testing identifies genetic disorders in only 20-30% of patients analysed, indicating a gap in knowledge of its genetic aetiology. Diagnosis relies on ECG, and risk stratification in BrS patients is challenging primarily because of the complexity of the issue. As a result, clinicians fail to provide the appropriate strategy for SCD prevention for many patients. Several variables and interventions are being studied to improve diagnostics and maximise patient protection. In addition, the scientific community must increase efforts to provide patient care according to knowledge and research for improving stratification of risk. In this article, the authors summarise contemporary evidence on clinical variables and provide an overview of future directions in risk stratification and SCD prevention.

引用

页码：45 / 49

页数：5

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