One-Pot Synthesis of Spheres-on-Sphere Silica Particles from a Single Precursor for Fast HPLC with Low Back Pressure

被引：60
作者：
Ahmed, Adham [1 ]
Ritchie, Harald [2 ]
Myers, Peter [1 ]
Zhang, Haifei [1 ]
机构：
[1] Univ Liverpool, Dept Chem, Liverpool L69 7ZD, Merseyside, England
[2] Thermo Fisher Sci, Runcorn WA7 1TA, Cheshire, England
来源：
ADVANCED MATERIALS | 2012年 / 24卷 / 45期
关键词：
PERFORMANCE LIQUID-CHROMATOGRAPHY; MONOLITHIC COLUMNS; MICROSPHERES; POLYMER; NANOPARTICLES; CARBON; GOLD; CORE;
D O I：
10.1002/adma.201202810
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Spheres-on-sphere (SOS) silica particles are prepared in a one-pot scalable synthesis from mercaptopropyltrimethoxysilane with hydrophilic polymer and cationic surfactant under alkaline conditions. The SOS particles exhibit solid-core porous-shell properties. The fast separation of small molecules and proteins with low back pressure are demonstrated by high-performance liquid chromatography (HPLC) for the columns packed with SOS-particles. [GRAPHICS] .
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收藏
页码：6042 / +
页数：8
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