Molecular diagnostics complementing morphology in superficial mesenchymal tumors

被引：9

作者：

Cheah, Alison L. ^{[1
]}

Goldblum, John R. ^{[1
]}

Billings, Steven D. ^{[1
]}

机构：

[1] Cleveland Clin, Dept Anat Pathol, Cleveland, OH 44195 USA

来源：

SEMINARS IN DIAGNOSTIC PATHOLOGY | 2013年 / 30卷 / 01期

关键词：

Molecular diagnostics; FISH; Angiomatoid fibrous histiocytoma; Clear cell sarcoma; Low-grade fibromyxoid sarcoma; Dermatofibrosarcoma protuberans; Postradiation angiosarcoma; Epithelioid hemangioendothelioma; Nodular fasciitis; Ewing sarcoma; CLEAR-CELL SARCOMA; GRADE FIBROMYXOID SARCOMA; IN-SITU HYBRIDIZATION; MALIGNANT FIBROUS HISTIOCYTOMA; ATYPICAL VASCULAR-LESIONS; POLYMERASE CHAIN-REACTION; SARCOMA/PRIMITIVE NEUROECTODERMAL TUMOR; COL1A1-PDGFB FUSION TRANSCRIPTS; DERMATOFIBROSARCOMA PROTUBERANS; EWING-SARCOMA;

D O I：

10.1053/j.semdp.2012.01.005

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Molecular techniques are increasingly important in the practice of surgical pathology. In soft tissue tumors, there are a number of tumors with recurring cytogenetic abnormalities. Knowledge of these abnormalities has furthered our understanding of these tumors and has also allowed development of molecular techniques to aid in the diagnosis. This review will focus on mesenchymal tumors with specific cytogenetic abnormalities that may present as a superficial tumor of the dermis or subcutis. (C) 2013 Elsevier Inc. All rights reserved.

引用

页码：95 / 109

页数：15

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