Bioactive chemical constituents of Cladiella species

被引：21
|
作者：
Ata, A
Ackerman, J
Bayoud, A
Radhika, P
机构：
[1] Univ Winnipeg, Dept Chem, Winnipeg, MB R3B 2E9, Canada
[2] Andhra Univ, Dept Pharmaceut Sci, Visakhapatnam 530003, Andhra Pradesh, India
来源：
HELVETICA CHIMICA ACTA | 2004年 / 87卷 / 03期
关键词：
D O I：
10.1002/hlca.200490056
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
From the methanolic extract of Cladiella sp., collected from the Andaman Island, India, a new sesquiterpene, cladidiol (2), and three known diterpenes, cladiellaperoxide (3), (6E)-2alpha,9alpha-epoxyeunicella-6,11(12)-dien-3beta-ol (4), and polyanthellin A (5) were isolated. The structures of these compounds were established by extensive spectroscopic studies. Compound 2 exhibited modest acetylcholinesterase-inhibition activity, and compounds 3 - 5 showed antibacterial activities against Streptococcus pyogenes, Escherichia coli, and Pseudomonas aeruginosa.
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收藏
页码：592 / 597
页数：6
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