Copper-Catalyzed Aromatic C-H Bond Cyanation by C-CN Bond Cleavage of Inert Acetonitrile

被引：103

作者：

Kou, Xuezhen ^{[2
,3
]}

Zhao, Mengdi ^{[1
]}

Qiao, Xixue ^{[1
]}

Zhu, Yamin ^{[1
]}

Tong, Xiaofeng ^{[2
,3
]}

Shen, Zengming ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, Shanghai 200240, Peoples R China

[2] E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China

[3] E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2013年 / 19卷 / 50期

关键词：

acetonitrile; catalysis; copper; cyanation; disilane; CARBON-CARBON BONDS; DIRECT TRANSFORMATION; AMMONIUM IODIDE; RECENT PROGRESS; BENZYL CYANIDE; METHYL ARENES; ARYL HALIDE; PALLADIUM; ACTIVATION; NITRILES;

D O I：

10.1002/chem.201303637

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cut and paste! A Cu-catalyzed aromatic C-H cyanation with acetonitrile as the nitrile source by C-CN cleavage has been developed (see scheme; TMEDA=N,N,N′,N′-tetramethylethylenediamine). The reaction is catalytic in copper, and it is found that using (Me3Si)2 as an additive plays a critical role in promoting C-CN cleavage and enhancing the reaction rate. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：16880 / 16886

页数：7

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