SEPARATION OF CLUSIANONE FROM CLUSIA FLUMINENSIS PLANCH. AND TRIANA (CLUSIACEAE) BY HIGH SPEED COUNTER-CURRENT CHROMATOGRAPHY (HSCCC)

被引：7

作者：

Anholeti da Silva, Maria Carolina ^{[1
]}

Heringer, Alan Patrick ^{[2
]}

Figueiredo, Maria Raquel ^{[2
]}

de Paiva, Selma Ribeiro ^{[1
]}

机构：

[1] Univ Fed Fluminense, Setor Bot Posgrad Ciencias Aplicadas & Prod Para, Rio De Janeiro, RJ, Brazil

[2] Far Manguinhos Fundacao Oswaldo Cruz, Lab Quim Prod Nat, Rio De Janeiro, RJ, Brazil

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES | 2012年 / 35卷 / 16期

关键词：

benzophenones; Clusia; Clusia fluminensis; Clusiaceae; clusianone; HSCCC; POLYISOPRENYLATED BENZOPHENONES; BRASILIENSIS; DERIVATIVES; CHEMISTRY; GENUS;

D O I：

10.1080/10826076.2011.631261

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The floral resins of the genus Clusia L. (Clusiaceae Lindl.) mainly consist of polyisoprenylated benzophenones, a class of substances which is noteworthy due to its broad spectrum of biological activities. This paper describes the isolation of clusianone from the male flowers of Clusia fluminensis Planch. & Triana, a native species from the Brazilian coast, using, for the first time, high-speed counter-current chromatography with a nonaqueous solvent system composed of n-hexane-acetonitrile-methanol (2:1.25:0.5, v/v/v) in 2 hr, with purity higher than 90%.

引用

页码：2313 / 2321

页数：9

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