Management of ulcerative colitis in a real-life setting: An Italian multicenter, prospective, observational AIGO study

被引：4

作者：

Scribano, Maria Lia ^{[1
]}

Papi, Claudio ^{[2
]}

Costa, Francesco ^{[3
]}

Bortoli, Aurora ^{[4
]}

Bortoluzzi, Francesco ^{[5
]}

Buscarini, Elisabetta ^{[6
]}

Cappello, Maria ^{[7
]}

Caserta, Luigi ^{[8
]}

Cortelezzi, Claudio ^{[9
]}

Ferronato, Antonio ^{[10
]}

Manguso, Francesco ^{[11
]}

Mazzuoli, Silvia ^{[12
]}

Orzes, Nicoletta ^{[13
]}

Kohn, Anna ^{[1
]}

Balatsinu, Chrysanthi ^{[14
]}

Ceccarelli, Linda ^{[15
]}

Cedola, Marco ^{[16
]}

Faggiani, Roberto ^{[17
]}

Geccherle, Andrea ^{[18
]}

Gigliozzi, Alessandro ^{[19
]}

Gullotta, Renzo ^{[20
]}

Lorenzetti, Roberto ^{[21
]}

Lupinacci, Guido ^{[22
]}

Mastronardi, Mauro ^{[23
]}

Mocci, Giammarco ^{[24
]}

Scarpulla, Giuseppe ^{[25
]}

Shalling, Renzo ^{[26
]}

Sozzi, Michele ^{[27
]}

Tarantino, Ottaviano ^{[28
]}

机构：

[1] AO San Camillo Forlanini, Gastroenterol Unit, Cir Convallaz Gianicolense 87, I-00152 Rome, Italy

[2] San Filippo Neri Hosp, Gastroenterol Unit, Rome, Italy

[3] AOUP, Gastroenterol Unit, Pisa, Italy

[4] UAO G Salvini, Gastroenterol Unit, Rho, Italy

[5] Ulss 3 Serenissima, Gastroenterol Unit, Venice, Italy

[6] Maggiore Hosp, Gastroenterol Unit, Crema, Italy

[7] Univ Palermo, DIBIMIS, Gastroenterol & Hepatol Sect, Palermo, Italy

[8] San Martino Hosp, Gastroenterol Unit, Genoa, Italy

[9] ASST Settelaghi, Gastroenterol Unit, Varese, Italy

[10] ULSS 7 Pedemontana, PO Alto Vicentino, Endoscopy Unit, Vicenza, Italy

[11] Cardarelli Hosp, Gastroenterol Unit, Naples, Italy

[12] San Nicola Pellegrino Hosp, Gastroenterol Unit, Trani, Italy

[13] PO Gorizia Pordenone, Gastroenterol Unit, Gorizia, Italy

[14] ASUR Marche AV3, Endoscopy Unit, Po Civitanova Marche, MC, Italy

[15] AOUP Cisanello Hosp, Gastroenterol Unit, Pisa, Italy

[16] Spaziani Hosp, Gastroenterol Unit, Frosinone, Italy

[17] PO Belcolle, Gastroenterol Unit, Viterbo, Italy

[18] SacroCuore Don Calabria Hosp, IBD Unit, Negrar, VR, Italy

[19] San Camillo De Lellis Hosp, Gastroenterol Unit, Rieti, Italy

[20] Clin San Carlo, Gastroenterol Unit, Paderno Dugnano, MI, Italy

[21] Nuovo Regina Margherita Hosp, Gastroenterol Unit, Rome, Italy

[22] Maggiore Hosp, Gastroenterol Unit, Crema, Italy

[23] IRCSS De Bellis, Endoscopy Unit, Castellana Grotte, BA, Italy

[24] AO G Brotzu, Gastroenterol Unit, Cagliari, Italy

[25] PO Maddalena Raimondi San Cataldo, Gastroenterol Unit, Caltanissetta, Italy

[26] Vimercate Hosp, Endoscopy Unit, Vimercate, MB, Italy

[27] Cattinara Hosp, Gastroenterol Unit, Trieste, Italy

[28] ASL 11, Gastroenterol Unit, Empoli, FI, Italy

来源：

DIGESTIVE AND LIVER DISEASE | 2019年 / 51卷 / 03期

关键词：

Clinical practice; Management; Real-life; Ulcerative colitis; INFLAMMATORY-BOWEL-DISEASE; ORAL BECLOMETASONE DIPROPIONATE; EVIDENCE-BASED CONSENSUS; DOUBLE-BLIND; 5-AMINOSALICYLIC ACID; INCEPTION COHORT; THERAPY; GUIDELINES; DIAGNOSIS; WORK;

D O I：

10.1016/j.dld.2018.08.006

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background: No data are available on the variability in the clinical management of ulcerative colitis (UC) patients by Italian gastroenterologists. Therefore, improving the standards of UC care as provided by the National Welfare Clinical Path (PDTA), in accordance with the European Crohn's and Colitis Organization (ECCO) guidelines for UC, is not easy. Aims: To assess the management of UC by Italian gastroenterologists in a real-life setting taking into account its variability. Methods: This prospective, cross-sectional, observational study included IBD-specialized gastroenterologists (GSIBDs) and general gastroenterologists (GGs) working in Italian public hospital units. Consecutive patients with an UC flare were enrolled and the medical treatment evaluated. For each center, the physician in charge of the study (16 GSIBDs and 10 GGs) was administered two electronic questionnaires. Results: Among 26 units, 573 UC patients were enrolled. Good adherence to the European guidelines was reported; GSIBDs reported greater adherence than GGs with a higher prescription of rectal and combination therapy in mild to moderate distal disease and a higher rate of hospitalization in severe UC. Conclusion: The management of UC by Italian gastroenterologists in clinical practice is good according to the ECCO consensus recommendations, though some discrepancies are present between GSIBDs and GGs. (C) 2018 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

引用

页码：346 / 351

页数：6

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