Spectral power differences in the brain activity of growth-restricted and normal fetuses

被引：6

作者：

Eswaran, Hari ^{[1
]}

Govindan, Rathinaswamy B. ^{[1
]}

Haddad, Naim I. ^{[2
]}

Siegel, Eric R. ^{[3
]}

Preissl, Hubert T. ^{[1
,4
]}

Murphy, Pamela ^{[1
]}

Lowery, Curtis L. ^{[1
]}

机构：

[1] Univ Arkansas Med Sci, Dept Obstet & Gynecol, Little Rock, AR 72205 USA

[2] Univ Arkansas Med Sci, Dept Neurol, Little Rock, AR 72205 USA

[3] Univ Arkansas Med Sci, Dept Biostat, Little Rock, AR 72205 USA

[4] Univ Tubingen, MEG Ctr, Tubingen, Germany

来源：

EARLY HUMAN DEVELOPMENT | 2012年 / 88卷 / 06期

基金：

美国国家卫生研究院;

关键词：

Fetus; Neonates; EEG; MEG; Growth-restricted; Brain activity; NEWBORN ENCEPHALOPATHY; RISK-FACTORS; MAGNETOENCEPHALOGRAPHY; INFANTS; TERM;

D O I：

10.1016/j.earlhumdev.2011.09.003

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Using non-invasive fetal magnetoencephalography (fMEG), we investigated spontaneous brain activity in 28 fetuses diagnosed with intrauterine growth restriction (IUGR) and compared the results to 47 normal-growth fetuses. The fetal gestational age ranged from 28 to 39 weeks with post-natal recordings obtained on 17 of the IUGR fetuses. Power spectrum was computed and was divided into four frequency bands. A significant difference in the relative spectral power in delta, theta and beta bands (P < 0.01) was observed only in the 28-32 week gestation age group with alpha band showing a similar trend (P=0.054). This observation suggests that growth restriction may have a more pronounced effect on the fetal brain in early gestation. Larger population studies could reveal the potential value of fMEG as an additional surveillance tool for growth-restricted fetuses. (C) 2011 Elsevier Ireland Ltd. All rights reserved.

引用

页码：451 / 454

页数：4

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