Graphical models for genetic analyses

被引：91
作者：
Lauritzen, SL [1 ]
Sheehan, NA [1 ]
机构：
[1] Aalborg Univ, Dept Math Sci, DK-9220 Aalborg, Denmark
来源：
STATISTICAL SCIENCE | 2003年 / 18卷 / 04期
关键词：
Bayesian network; forensic genetics; linkage analysis; local computation; peeling; probability propagation; QTL analysis;
D O I：
10.1214/ss/1081443232
中图分类号：
O21 [概率论与数理统计]; C8 [统计学];
学科分类号：
020208 ; 070103 ; 0714 ;
摘要：
This paper introduces graphical models as a natural environment in which to formulate and solve problems in genetics and related areas. Particular emphasis is given to the relationships among various local computation algorithms which have been developed within the hitherto mostly separate areas of graphical models and genetics. The potential of graphical models is explored and illustrated through a number of example applications where the genetic element is substantial or dominating.
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收藏
页码：489 / 514
页数：26
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