Deep Endometriosis and Infertility: What Is the Impact of Surgery?

被引：16

作者：

Daniilidis, Angelos ^{[1
]}

Angioni, Stefano ^{[2
]}

Di Michele, Stefano ^{[2
]}

Dinas, Konstantinos ^{[1
]}

Gkrozou, Fani ^{[3
]}

D'Alterio, Maurizio Nicola ^{[2
]}

机构：

[1] Aristotle Univ Thessaloniki, Hippokratio Hosp, Dept Obstet & Gynecol, Thessaloniki 54642, Greece

[2] Univ Cagliari, Dept Surg Sci, Cittadella Univ Blocco 1,Asse Didatt Medicna P2, I-09042 Cagliari, Italy

[3] Univ Ioannina, Univ Clin Obstet & Gynecol, Ioannina 45110, Greece

来源：

JOURNAL OF CLINICAL MEDICINE | 2022年 / 11卷 / 22期

关键词：

deep endometriosis; infertility; surgery; ART; MAR; IN-VITRO FERTILIZATION; ANTI-MULLERIAN HORMONE; INFILTRATING ENDOMETRIOSIS; COLORECTAL ENDOMETRIOSIS; SURGICAL-MANAGEMENT; FOLLOW-UP; SYMPTOMATIC ENDOMETRIOSIS; SEGMENTAL RESECTION; PREGNANCY RATE; DISC EXCISION;

D O I：

10.3390/jcm11226727

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In women with deep endometriosis, the spontaneous fertility rate might range from 2 to 10%. The optimal management of these women is still an area of debate. Therefore, this review aims to explore the literature on the impact of deep endometriosis surgery on reproductive outcomes and pregnancy rates in women with and without prior infertility. A total of 392 articles were identified through database searching. Twenty-three studies were eligible to be included in the review. A total of 1548 women were identified, 814 of whom became pregnant, with a mean pregnancy rate of 52.6% (95% CI 49.7-63%). Our review suggests that surgery may improve fertility outcomes. Due to the variability in the studies, it is impossible to stratify fertility outcomes of surgery by the localization of deep endometriosis. More investigations are needed to determine whether surgical management should be first-intention or limited to the failure of medically assisted reproduction treatment.

引用

页数：23

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