Calcium phosphate-based cements: clinical needs and recent progress

被引：106

作者：

Sugawara, Akiyoshi ^{[1
]}

Asaoka, Kenzo ^{[2
]}

Ding, Shinn-Jyh ^{[3
,4
]}

机构：

[1] Nihon Univ, Sch Dent, Sugawara Dent Clin, Tokyo 101, Japan

[2] Univ Tokushima, Sch Dent, Inst Hlth Biosci, Dept Biomat & Bioengn, Tokushima, Tokushima 7708504, Japan

[3] Chung Shan Med Univ Hosp, Dept Dent, Taichung 402, Taiwan

[4] Chung Shan Med Univ Hosp, Inst Oral Sci, Taichung 402, Taiwan

来源：

JOURNAL OF MATERIALS CHEMISTRY B | 2013年 / 1卷 / 08期

关键词：

ENDOTHELIAL GROWTH-FACTOR; BONE CEMENTS; COMPRESSIVE STRENGTH; PHYSICOCHEMICAL PROPERTIES; HYDROXYAPATITE CEMENT; PHYSICAL-PROPERTIES; DRUG-DELIVERY; SCAFFOLDS; COMPOSITE; BRUSHITE;

D O I：

10.1039/c2tb00061j

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Although autografts are considered to be the current gold standard, there is still clinical demand for synthetic bone graft substitutes. Calcium phosphate cements (CPCs) have many favourable properties that support their clinical use in the repair of bone defects. Although the translation of CPCs from the bench to the bedside has been quite successful, some issues remain. This review article provides an overview of the recent progress in the development of CPC-based materials and also emphasises the challenges facing clinical applications. The next generation of CPCs with unique properties is emerging for specific clinical applications.

引用

页码：1081 / 1089

页数：9

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