A novel process for recovery and refining of L-lactic acid from fermentation broth

被引:48
作者
Chen, Lijun [1 ]
Zeng, Aiwu [1 ]
Dong, Haibo [1 ]
Li, Qi [1 ]
Niu, Congcong [1 ]
机构
[1] Tianjin Univ, Sch Chem Engn & Technol, State Key Lab Chem Engn, Tianjin 300072, Peoples R China
关键词
Fermentation broth; L-lactic acid; Solvent extraction procedure; Refining process; Centrifugal short-path distillation; DISTILLATION; EXTRACTION;
D O I
10.1016/j.biortech.2012.02.100
中图分类号
S2 [农业工程];
学科分类号
0828 ;
摘要
This paper introduces a novel process for recovery and refining of L-lactic acid from a fermentation broth. The use of a solvent extraction step, in the novel approach, has significant impacts on the following centrifugal short-path distillation conditions (operating pressure, evaporator temperature and feed flow rate). As the conditions were varied, the L-lactic acid purity and yield in the distillate were monitored. For the purpose of comparison, a series of experiments were also carried out using the existing purification process. The results showed that both of the two processes can obtain L-lactic acid with a high purity around 91.3%, while the yield obtained using the novel process reached 61.73%, which was about 20.43% higher than that using the existing process. Additionally, multiple-pass distillation observed special attention by improving the yield up to 74.63%. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:280 / 284
页数:5
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