Reactions of Arynes with Sulfoximines: Formal Sulfinylamination vs. N-Arylation

被引：35

作者：

Yoshida, Suguru ^{[1
]}

Nakajima, Hana ^{[1
]}

Uchida, Keisuke ^{[1
]}

Yano, Takahisa ^{[1
]}

Kondo, Masakazu ^{[2
]}

Matsushita, Takeshi ^{[2
]}

Hosoya, Takamitsu ^{[1
]}

机构：

[1] Tokyo Med & Dent Univ, Inst Biomat & Bioengn, Lab Chem Biosci, Chiyoda Ku, 2-3-10 Kanda Surugadai, Tokyo 1010062, Japan

[2] JNC Petrochem Corp, Ichihara Res Ctr, 5-1 Goikaigan, Ichihara, Chiba 2908551, Japan

来源：

CHEMISTRY LETTERS | 2017年 / 46卷 / 01期

关键词：

Aryne; Sulfoximine; Thioamination; MULTICOMPONENT COUPLING REACTION; FACILE SYNTHESIS; BOND FORMATION; NUCLEOPHILIC-ADDITION; EXCHANGE-REACTION; GENERATION; ARYL; INSERTION; BENZYNE; ACTIVATION;

D O I：

10.1246/cl.160865

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reactions of arynes with sulfoximines are reported. The fate of these reactions depends on the substituents of the sulfoximines. S, S-Diarylsulfoximines reacted with arynes to selectively afford o-sulfinylanilines, whereas a simple N-arylation reaction was observed when S-alkyl-S-aryl-or S, S-dialkylsulfoximine was used to selectively afford the corresponding N-arylated sulfoximines.

引用

页码：77 / 80

页数：4

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