Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not

被引：10

作者：

Argiro, Alessia ^{[1
]}

Del Franco, Annamaria ^{[1
]}

Mazzoni, Carlotta ^{[1
]}

Allinovi, Marco ^{[1
]}

Tomberli, Alessia ^{[1
]}

Tarquini, Roberto ^{[2
]}

Di Mario, Carlo ^{[3
]}

Perfetto, Federico ^{[1
]}

Cappelli, Francesco ^{[1
]}

Zampieri, Mattia ^{[1
]}

机构：

[1] Careggi Univ Hosp, Tuscan Reg Amyloidosis Ctr, I-50134 Florence, Italy

[2] San Giuseppe Hosp, Dept Internal Med 1, I-50053 Empoli, Italy

[3] Careggi Univ Hosp, Struct Intervent Cardiol Dept, I-50134 Florence, Italy

来源：

BIOMEDICINES | 2022年 / 10卷 / 11期

关键词：

arrhythmias; atrial fibrillation; pacemaker implantation; cardiac amyloidosis; PRESERVED EJECTION FRACTION; LIGHT-CHAIN AMYLOIDOSIS; LATE GADOLINIUM ENHANCEMENT; ATRIAL-FIBRILLATION; HEART-FAILURE; CARDIOVERTER-DEFIBRILLATOR; TRANSTHYRETIN AMYLOIDOSIS; INTRACARDIAC THROMBOSIS; PACEMAKER IMPLANTATION; SINUS RHYTHM;

D O I：

10.3390/biomedicines10112888

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cardiac amyloidosis (CA), caused by the deposition of insoluble amyloid fibrils, impairs different cardiac structures, altering not only left ventricle (LV) systo-diastolic function but also atrial function and the conduction system. The consequences of the involvement of the cardiac electrical system deserve more attention, as well as the study of the underlying molecular mechanisms. This is an issue of considerable interest, given the conflicting data on the effectiveness of conventional antiarrhythmic strategies. Therefore, this review aims at summarizing the arrhythmic burden related to CA and the available evidence on antiarrhythmic treatment in this population.

引用

页数：15

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