Italian multicenter experience with flow-diverter devices for intracranial unruptured aneurysm treatment with periprocedural complications-a retrospective data analysis

被引：149

作者：

Briganti, Francesco ^{[1
]}

Napoli, Manuela ^{[1
]}

Tortora, Fabio ^{[2
]}

Solari, Domenico ^{[3
]}

Bergui, Mauro ^{[4
]}

Boccardi, Edoardo ^{[5
]}

Cagliari, Enrico ^{[6
]}

Castellan, Lucio ^{[7
]}

Causin, Francesco ^{[8
]}

Ciceri, Elisa ^{[9
]}

Cirillo, Luigi ^{[10
]}

De Blasi, Roberto ^{[11
]}

Delehaye, Luigi ^{[12
]}

Di Paola, Francesco ^{[13
]}

Fontana, Andrea ^{[14
]}

Gasparotti, Roberto ^{[15
]}

Guidetti, Giulio ^{[16
]}

Divenuto, Ignazio ^{[17
]}

Iannucci, Giuseppe ^{[18
]}

Isalberti, Maurizio ^{[19
]}

Leonardi, Marco ^{[10
]}

Lupo, Fernando ^{[20
]}

Mangiafico, Salvatore ^{[21
]}

Manto, Andrea ^{[22
]}

Menozzi, Roberto ^{[23
]}

Muto, Mario ^{[24
]}

Nuzzi, Nunzio Paolo ^{[25
]}

Papa, Rosario ^{[19
]}

Petralia, Benedetto ^{[26
]}

Piano, Mariangela ^{[5
]}

Resta, Maurizio ^{[27
]}

Padolecchia, Riccardo ^{[28
]}

Saletti, Andrea ^{[29
]}

Sirabella, Giovanni ^{[30
]}

Bolge, Luca Piero Valvassori ^{[5
]}

机构：

[1] Univ Naples Federico II, Intervent Neuroradiol Unit, I-80131 Naples, Italy

[2] Univ Naples 2, Inst Radiol, Naples, Italy

[3] Univ Naples Federico II, Div Neurosurg, I-80131 Naples, Italy

[4] Univ Turin, Neuroradiol Div, Turin, Italy

[5] Osped Niguarda Ca Granda, Intervent Neuroradiol Div, Milan, Italy

[6] Osped Angelo, Neuroradiol Unit, Venice, Italy

[7] San Martino Hosp, Dept Neuroradiol, Genoa, Italy

[8] City Hosp, Neuroradiol Div, Vicenza, Italy

[9] Fdn IRCCS Ist Neurol Carlo Besta, Neuroradiol Unit, Milan, Italy

[10] Bellaria Maggiore Hosp, Dept Neuroradiol, Bologna, Italy

[11] Univ Hosp, Unit Neuroradiol & Intervent Radiol, Bari, Italy

[12] San Giovanni Bosco Hosp, Unit Neuroradiol, Naples, Italy

[13] Treviso Hosp, Dept Neuroradiol, Treviso, Italy

[14] IRCCS Casa Sollievo Sofferenza, Unit Biostat, San Giovanni Rotondo, Italy

[15] Univ Brescia, Osped Civili, Inst Neuroradiol, Brescia, Italy

[16] Univ Roma La Sapienza, Sch Med, Rome, Italy

[17] Amedeo Avogadro Univ, Dept Radiol, Novara, Italy

[18] Vicenza Hosp, Dept Neuroradiol, Vicenza, Italy

[19] Osped Maggiore Policlin, Fdn IRCCS Ca Granda, Milan, Italy

[20] V Fazzi Hosp, Dept Neuroradiol, Lecce, Italy

[21] Careggi Hosp, Dept Neuroradiol, Florence, Italy

[22] Umberto I Hosp, Dept Neuroradiol, Salerno, Italy

[23] Univ Parma, Dept Neuroradiol, I-43100 Parma, Italy

[24] A Cardarelli Hosp, Neuroradiol Unit, Naples, Italy

[25] EO Osped Galliera, Unit Diagnost & Intervent Neuroradiol, Genoa, Italy

[26] Udine Univ Hosp, Dept Neuroradiol, Udine, Italy

[27] SS Annunziata Hosp, Dept Radiol & Neuroradiol, Taranto, Italy

[28] Santa Corona Hosp, Neuroradiol Unit, Sanova, Italy

[29] St Anna Hosp, Neuroradiol Unit, Ferrara, Italy

[30] Loreto Nuovo Hosp, Neuroradiol Unit, Naples, Italy

来源：

NEURORADIOLOGY | 2012年 / 54卷 / 10期

关键词：

Flow diverter device; Pipeline embolization device; Silk embolization device; Intracranial aneurysms; Endovascular treatment; PIPELINE EMBOLIZATION DEVICE; CEREBRAL ANEURYSMS; NEUROFORM STENT; ENDOVASCULAR TREATMENT; RECONSTRUCTION; COILING; GIANT;

D O I：

10.1007/s00234-012-1047-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report the experiences of 25 Italian centers, analyzing intra- and periprocedural complications of endovascular treatment of intracranial aneurysms using Silk (Balt Extrusion, Montmorency, France) and pipeline embolization devices (EV3 Inc, Irvine California). Two hundred seventy-three patients with 295 cerebral aneurysms, enrolled in 25 centers in Italy and treated with the new flow-diverter devices, were evaluated; 142 patients were treated with Silk and 130 with pipeline (in one case, both devices were used). In 14 (5.2 %) cases devices were used with coils. Aneurysm size was > 15 mm in 46.9 %, 5-15 mm in 42.2 %, and < 5 mm in 10.8 %. Aneurysm locations were supraclinoid internal carotid artery (ICA) in 163 cases (55.2 %), cavernous ICA in 76 (25.7 %), middle cerebral artery in 11 (3.7 %), PCoA in 6 (2 %), and ACoA in 2 (0.7 %); the vertebrobasilar system accounted for 32 cases (10.8 %) and PCA in 5 (1.7 %). Technical adverse events occurred with 59 patients (21.6 %); 5 patients died after ischemic events, 10 to hemorrhagic complications, and 1 from external ventricular drain positioning. At 1 month, morbidity and mortality rates were 3.7 % and 5.9 %, respectively Our retrospective study confirms that morbidity and mortality rates in treatment with FDD of unruptured wide-neck or untreatable cerebral aneurysms do not differ from those reported in the largest series.

引用

页码：1145 / 1152

页数：8