Miniaturized module with biosensors for potentiometric determination of urea

被引：8

作者：

Grabowska, Ilona ^{[1
]}

Ksok, Ewa ^{[1
]}

Wyzkiewicz, Iwona ^{[2
]}

Chudy, Michal ^{[1
]}

机构：

[1] Warsaw Univ Technol, Dept Analyt Chem, PL-00664 Warsaw, Poland

[2] Inst Elect Mat Technol, PL-01919 Warsaw, Poland

来源：

MICROCHIMICA ACTA | 2009年 / 164卷 / 3-4期

关键词：

Electrochemical detection; Urea determination; PDMS; Ceramics; Hybrid microtechnology; Flow-through analysis; MICROSYSTEM; ELECTRODES; SYSTEM; TECHNOLOGY; MEMBRANE;

D O I：

10.1007/s00604-008-0108-0

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

We describe the construction of a miniaturized module which allows carrying out potentiometric urea determination with the usage of biosensors. The module was fabricated using new hybrid technologies developed in our group which combine ceramic and polymeric materials. Its simplicity and easy way of preparation makes the system very useful for analytical measurements in a flow mode. Application of urease-modified polymer membranes deposited on silver screen-printed electrodes in the module allows to determine urea concentration in clinical range. Moreover, it is a very promising construction for other applications in that other enzymes can be immobilized and various bioanalytes can be determined using this module.

引用

页码：299 / 305

页数：7

共 23 条

[1]

BAUER W, 2007, INTERCERAM, V56, P1

[2]

BUTLER A R, 1982, Trends in Analytical Chemistry, V1, P120, DOI 10.1016/0165-9936(82)80011-3

[3]

CHUDY M, 2006, P SPIE INT SOC OPT E, V6348

[4] Analysis of dialysate fluids with the use of a potentiometric electronic tongue [J].

Ciosek, Patrycja ;

Grabowska, Ilona ;

Brzozka, Zbigniew ;

Wroblewski, Wojciech .

MICROCHIMICA ACTA, 2008, 163 (1-2) :139-145

[5]

DellaCiana L, 1996, CLIN CHEM, V42, P1079

[6] SPECTROPHOTOMETRIC DETERMINATION OF UREA AND AMMONIA IN NATURAL WATERS WITH HYPOCHLORITE AND PHENOL [J].

EMMET, RT .

ANALYTICAL CHEMISTRY, 1969, 41 (12) :1648-&

[7]

Fibbioli M, 2000, ELECTROANAL, V12, P1286, DOI 10.1002/1521-4109(200011)12:16<1286::AID-ELAN1286>3.0.CO

[8]

2-Q

[9]

FRANCIS PS, 1982, TRENDS ANAL CHEM, V1, P120

[10] LTCC based microfluidic system with optical detection [J].

Golonka, LJ ;

Roguszczak, H ;

Zawada, T ;

Radojewski, J ;

Grabowska, I ;

Chudy, M ;

Dybko, A ;

Brzozka, Z ;

Stadnik, D .

SENSORS AND ACTUATORS B-CHEMICAL, 2005, 111 :396-402

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