Family Herpesviridae and neuroinfections: current status and research in progress

被引：24

作者：

de Souza Carneiro, Vanessa Cristine ^{[1
]}

Pereira, Jessica Goncalves ^{[1
]}

de Paula, Vanessa Salete ^{[1
]}

机构：

[1] Fundacao Oswaldo Cruz Fiocruz, Inst Oswaldo Cruz, Lab Virol Mol, Rio De Janeiro, RJ, Brazil

来源：

MEMORIAS DO INSTITUTO OSWALDO CRUZ | 2022年 / 117卷

关键词：

herpesvirus; neuroinfection; neurodegeneration; EPSTEIN-BARR-VIRUS; PARKINSONS-DISEASE; GENOME SEQUENCE; DNA-SEQUENCES; CYTOMEGALOVIRUS; INFECTION; ZOSTER; RISK; IMMUNOCOMPETENT; IDENTIFICATION;

D O I：

10.1590/0074-02760220200

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

This article addresses the relationship between human herpesviruses (HHVs) and neuroinfections. Alphaherpesviruses, betaherpesviruses and gammaherpesviruses are neurotropic viruses that establish latency and exhibit reactivation capacity. Encephalitis and meningitis are common in cases of HHV. The condition promoted by HHV infection is a purported trigger for certain neurodegenerative diseases. Ongoing studies have identified an association between HSV-1 and the occurrence of Alzheimer???s disease, multiple sclerosis and infections by HHV-6 and Epstein-Barr virus. In this review, we highlight the importance of research investigating the role of herpesviruses in the pathogenesis of diseases that affect the nervous system and describe other studies in progress.

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页数：8

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