Microstructural evolution of super-clean reduced-activation martensitic steels irradiated with single-beam (Fe+) and sequential-beam (Fe+ plus He+) at 350 degrees C and 550 degrees C was studied. Sequential-beam irradiation induced smaller size and larger number density of precipitates compared to single-beam irradiation at 350 degrees C. The largest size of cavities was observed after sequential-beam irradiation at 550 degrees C. The segregation of Cr and W and depletion of Fe in carbides were observed, and the maximum depletion of Fe and enrichment of Cr occurred under irradiation at 350 degrees C. (C) 2013 Elsevier B.V. All rights reserved.