The Quest for Self-Identity: Not All Cancer Stem Cells Are the Same

被引:12
作者
Hjelmeland, Anita B. [1 ]
Rich, Jeremy N. [1 ]
机构
[1] Cleveland Clin, Lerner Res Inst, Dept Stem Cell Biol & Regenerat Med, Cleveland, OH 44195 USA
关键词
GLIOBLASTOMA; GLIOMA;
D O I
10.1158/1078-0432.CCR-12-1456
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A central critique of the cancer stem cell (CSC) hypothesis involves the robustness of CSC markers. Zorniak and colleagues suggest that different progenitor marker profiles can classify CSCs, and improved modeling of cellular hierarchies can be achieved by incorporating inter- and intratumoral diversity. Clin Cancer Res; 18(13); 3495-8. (C)2012 AACR.
引用
收藏
页码:3495 / 3498
页数:4
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