Cell Proliferation Tracking Using Graphene Sensor Arrays

被引：7

作者：

Daly, Ronan ^{[1
,2
]}

Kumar, Shishir ^{[1
,2
]}

Lukacs, Gyongyi ^{[1
,3
]}

Lee, Kangho ^{[1
,2
]}

Weidlich, Anne ^{[1
,2
]}

Hegner, Martin ^{[1
,3
]}

Duesberg, Georg S. ^{[1
,2
]}

机构：

[1] Univ Dublin Trinity Coll, CRANN, Dublin 2, Ireland

[2] Univ Dublin Trinity Coll, Sch Chem, Dublin 2, Ireland

[3] Univ Dublin Trinity Coll, Sch Phys, Dublin 2, Ireland

来源：

JOURNAL OF SENSORS | 2012年 / 2012卷

基金：

爱尔兰科学基金会;

关键词：

Cell proliferation - Escherichia coli - Graphene transistors;

D O I：

10.1155/2012/219485

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

The development of a novel label-free graphene sensor array is presented. Detection is based on modification of graphene FET devices and specifically monitoring the change in composition of the nutritive components in culturing medium. Microdispensing of Escherichia coli in medium shows feasibility of accurate positioning over each sensor while still allowing cell proliferation. Graphene FET device fabrication, sample dosing, and initial electrical characterisation have been completed and show a promising approach to reducing the sample size and lead time for diagnostic and drug development protocols through a label-free and reusable sensor array fabricated with standard and scalable microfabrication technologies.

引用

页数：7

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