Chemical aspects of influence of medical drugs on organism functions

被引：3
作者：
Granik, VG [1 ]
机构：
[1] State Sci Ctr Russian Federat NIOPIK, Moscow 103787, Russia
来源：
RUSSIAN CHEMICAL BULLETIN | 2001年 / 50卷 / 08期
关键词：
pharmacology; drugs; biological membranes; agonists; antagonists; inhibitors; mediators; receptors; enzymes; nitric oxide;
D O I：
10.1023/A:1012720620339
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Some fundamental problems of pharmacology important for setting investigations dealing with the search for new effective drugs are considered. The ways of introduction of drugs into the body, the types and functions of biological membranes, mediators of central and peripheral nervous systems, various receptor systems, and enzyme inhibitors are discussed.
引用
收藏
页码：1356 / 1378
页数：23
相关论文
共 34 条
[1]  
ALBERT A, 1989, IZBIRATELNAYA TOKSIC, V1
[2]  
ALTSHULER RA, 1976, ZH VSES KHIM OVA+, V30, P7
[3]  
BARLOW R, 1959, VVEDENIE KHIMICHESKU
[4]  
CANNON JG, 1999, PHARM CHEM
[5]   3,5-dihydro-4H-2,3-benzodiazepine-4-thiones:: A new class of AMPA receptor antagonists [J].
Chimirri, A ;
De Sarro, G ;
De Sarro, A ;
Gitto, R ;
Quartarone, S ;
Zappalà, M ;
Constanti, A ;
Libri, V .
JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (18) :3409-3416
[6]   Synthesis and pharmacology of a new AMPA-kainate receptor agonist with potent convulsant activity [J].
Conti, P ;
De Amici, M ;
De Sarro, G ;
Stensbol, TB ;
Brauner-Osborne, H ;
Madsen, U ;
De Micheli, C .
JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (20) :3759-3762
[7]  
DANILOV AV, 2001, VOPR BIOL MED FARMAT, P50
[8]  
Granik VG, 1997, USP KHIM+, V66, P792
[9]  
GRANIK VG, 2001, LEKARSTVA FARMAKOLOG
[10]  
GRANIK VG, 1977, FARMAKOL TOKSIKOL, P31
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