The Science of Resilience: Implications for the Prevention and Treatment of Depression

被引：577

作者：

Southwick, Steven M. ^{[3
,4
]}

Charney, Dennis S. ^{[1
,2
]}

机构：

[1] Mt Sinai Med Ctr, Mt Sinai Sch Med, Dept Psychiat, Dept Neurosci, New York, NY 10029 USA

[2] Mt Sinai Med Ctr, Mt Sinai Sch Med, Dept Pharmacol & Syst Therapeut, New York, NY 10029 USA

[3] Yale Univ, Sch Med, West Haven, CT 06516 USA

[4] Yale Univ, Yale Child Study Ctr, US Dept Vet Affairs VA, Natl Ctr Posttraumat Stress Disorder,VA Connectic, West Haven, CT 06516 USA

来源：

SCIENCE | 2012年 / 338卷 / 6103期

关键词：

STRESS;

D O I：

10.1126/science.1222942

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Human responses to stress and trauma vary widely. Some people develop trauma-related psychological disorders, such as posttraumatic stress disorder (PTSD) and depression; others develop mild to moderate psychological symptoms that resolve rapidly; still others report no new psychological symptoms in response to traumatic stress. Individual variability in how animals and humans respond to stress and trauma depends on numerous genetic, developmental, cognitive, psychological, and neurobiological risk and protective factors.

引用

页码：79 / 82

页数：4

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