Cytokine gene expression in bone marrow and exogenous colony formation in mice (CBA x C57BL)F1.

被引：0

作者：

Poveschenko, AF ^{[1
]}

Yakushenko, EV ^{[1
]}

Korotkova, NA ^{[1
]}

Abramov, VV ^{[1
]}

Kozlov, VA ^{[1
]}

机构：

[1] Russian Acad Med Sci, Clin Immunol Res Inst, Novosibirsk, Russia

来源：

GEMATOLOGIYA I TRANSFUZIOLOGIYA | 2002年 / 47卷 / 02期

关键词：

cytokine gene expression; bone marrow; exogenous colony formation;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

It is shown that mRNA of interieukin-1beta (IL-1beta), interleukin-1beta receptor (IL-1beta-R), erythropoietin receptor (EP-R) are expressed in the bone marrow cells of intact (CBAxC57BI)F1 mice. An injection of exogenous recombinant EP stimulates EP-R mRNA expression in the above cells (p < 0,05) but does not affect a mRNA level of IL-1 beta, 1 beta-R in the bone marrow of the above mice (p < 0,05). Introduction of the same dose of erythropoietin reliably stimulates colony formation in the bone marrow evaluated by 8-day exogenous colonies (p < 0.05).

引用

页码：23 / 24

页数：2

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