Growing Perivascular Epithelioid Cell Tumor of the Liver Studied With Contrast-Enhanced Ultrasonography and Magnetic Resonance Imaging

Perivascular epithelioid cell tumors (PEComas) are mesenchymal tumors with a usually benign biological behavior.(1,2) Perivascular epithelioid cell tumors constitute a family of mesenchymal neoplasms that include angiomyolipoma (AML), lymphangioleiomyomatosis, clear cell "sugar" tumors of the lung, and clear cell myomelanocytic tumors, arising in visceral and soft tissue; all show the presence of a particular cell type, known as a perivascular epithelioid cell. Angiomyolipoma of the liver belongs to this family, usually shows a prevalent component of large epithelioid cells, and is most frequently a slow-growing benign lesion." We report a case of a rapidly growing fiver PEComa in a patient with melanoma. Contrast-enhanced ultrasonography (CEUS), magnetic resonance imaging (MRI) with a hepatospecific contrast medium, and histologic examination were per-formed. During the follow-up, the dimensional increase and history of melanoma led to surgery, and a PEComa with no signs of malignancy was confirmed.