Predictors of Chronic Total Occlusion in Nonculprit Artery in Patients With Acute Coronary Syndrome: Mean Platelet Volume and Uric Acid

被引：4

作者：

Kurtul, Alparslan ^{[1
]}

Yarlioglues, Mikail ^{[1
]}

Murat, Sani Namik ^{[1
]}

Celik, Ibrahim Etem ^{[1
]}

Demircelik, Muhammed Bora ^{[2
]}

Ocek, Adil Hakan ^{[1
]}

Duran, Mustafa ^{[1
]}

Ergun, Gokhan ^{[1
]}

Cetin, Mustafa ^{[3
]}

Ornek, Ender ^{[3
]}

机构：

[1] Ankara Educ & Res Hosp, Dept Cardiol, Ankara, Turkey

[2] Turgut Ozal Univ, Dept Cardiol, Fac Med, Ankara, Turkey

[3] Numune Educ & Res Hosp, Dept Cardiol, Ankara, Turkey

来源：

ANGIOLOGY | 2015年 / 66卷 / 06期

关键词：

chronic total occlusion; noninfarct-related artery; mean platelet volume; serum uric acid; acute coronary syndrome; ELEVATION MYOCARDIAL-INFARCTION; LONG-TERM MORTALITY; ENDOTHELIAL DYSFUNCTION; CARDIOVASCULAR-DISEASE; PROGNOSTIC IMPACT; INTERVENTION; RISK; ATHEROSCLEROSIS; ANGIOPLASTY; ADMISSION;

D O I：

10.1177/0003319714542998

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Chronic total occlusion (CTO) in a noninfarct-related artery (non-IRA) is an independent predictor of mortality in acute coronary syndrome (ACS). Mean platelet volume (MPV) and serum uric acid (SUA) are associated with cardiovascular events in ACS. We investigated the relationship between the presence of non-IRA-CTO with MPV and SUA levels in patients with ACS. Patients (n = 1024) who underwent urgent coronary angiography for ACS were included in this study. Blood samples were drawn on admission. Patients were categorized into 2 groups: non-IRA-CTO (-) and non-IRA-CTO (+). The MPV and SUA levels on admission were significantly higher in the non-IRA-CTO (+) group than in the non-IRA-CTO (-) group (P < .001). At multivariate analysis, MPV (odds ratio [OR]: 4.705, P < .001) and SUA (OR: 2.535, P < .001) were independent predictors of non-IRA-CTO together with age, hemoglobin, ejection fraction, and non-ST-segment elevation ACS. The MPV and SUA levels were significant and independent predictors for the presence of non-IRA-CTO in patients with ACS.

引用

页码：553 / 559

页数：7

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