Epigenetics of Alzheimer's Disease and Frontotemporal Dementia

被引：24
|
作者：
Veerappan, Chendhore S. [1 ]
Sleiman, Sama [2 ]
Coppola, Giovanni [1 ,3 ]
机构：
[1] Univ Calif Los Angeles, David Geffen Sch Med, Semel Inst Neurosci & Human Behav, Los Angeles, CA 90095 USA
[2] Cornell Univ, Weill Med Coll, Burke Res Ctr, White Plains, NY USA
[3] Univ Calif Los Angeles, David Geffen Sch Med, Dept Neurol, Program Neurogenet, Los Angeles, CA 90095 USA
来源：
NEUROTHERAPEUTICS | 2013年 / 10卷 / 04期
关键词：
Neurodegeneration; Epigenetics; Alzheimer's disease; Frontotemporal dementia; Epigenetic drugs; Therapy; LONG NONCODING RNAS; AMYLOID PRECURSOR PROTEIN; SUBEROYLANILIDE HYDROXAMIC ACID; GAMMA-SECRETASE ACTIVITY; DNA METHYLATION; HISTONE ACETYLATION; MEMORY FORMATION; S-ADENOSYLHOMOCYSTEINE; GENETIC-HETEROGENEITY; HDAC INHIBITORS;
D O I：
10.1007/s13311-013-0219-0
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
This article will review the recent advances in the understanding of the role of epigenetic modifications and the promise of future epigenetic therapy in neurodegenerative dementias, including Alzheimer's disease and frontotemporal dementia.
引用
收藏
页码：709 / 721
页数：13
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